Pharmacognostical standardization and toxicity profile of the methanolic leaf extract of Plectranthus amboinicus (Lour) Spreng
Preeja G. Pillai, P. Suresh, Gayatri Aggarwal, Gaurav Doshi, Vidhi Bhatia
Pages: 76-81
Evaluation of antioxidant, antibacterial, antifungal and cytotoxic effects of Clausena suffruticosa ethanolic root extract
Md. Atiar Rahman, Joti Sankhar Chakma, Saiful Islam, Nazim Uddin Ahmed
Pages: 90-95
Synthesis, Cytotoxic and Anti-bacterial studies of some novel derivatives of N'-[(2E)-3-phenylprop-2-en-1-yl]-2-(quinolin-8-yloxy) acetohydrazide
Irfan A Mohammed, E.V.S. Subrahmanyam
Pages: 173-176
Cardioprotective, antioxidant activities and Phytochemical analysis by GC-MS of Gmelina arborea (GA) in Doxorubicin-induced myocardial necrosis in Albino rats
T.Vijay, M.S. Dhana Rajan, K.Sarumathy, S.Palani, K. Sakthivel
Pages: 198-204
Concerns regarding the safety and toxicity of medicinal plants - An overview
Philomena George
Pages: 40-44
Assessment of cytotoxicity, antibacterial activity and phytochemical screening of ethanol extract of Phyllanthus acidus L. (family: Euphorbiacceae) Bark
Subrata Kumar Biswas, Anusua Chowdhury, Joysree Das, Utpal Kumar Karmakar, Manik Chandra Shill, Sheikh Zahir Raihan
Pages: 112-114
Vediuppu Chendhuram: Oxide form of salt petre and its in vivo toxicological profile
V. Thanigavelan, V. Lakshmanakumar, V. Kaliyamurthi, G. Victor Rajamanickam
Pages: 150-158
Antioxidant, Cytotoxicity and Polyphenolic Content of Calotropis procera (Ait.) R. Br. Flowers
M. Rama Prabha, K. Vasantha
Pages: 136-140
Cytotoxic activity of methanolic extract of Artocarpus heterophyllus against A549, Hela and MCF-7 cell lines
Rajesh M.Patel, Sahil K. Patel
Pages: 167-171
Synthesis, characterization and anti-trypanosomal activity of R-(-)carvone and arylketones-thiosemi carbazones and toxicity against Artemia salina Leach
Bienvenu Glinma, Salome D. S. Kpoviessi, Raymond H. Fatondji, Fernand A. Gbaguidi, Coco N. Kapanda, Joanne Bero, Didier M. Lambert, Veronique Hannaert, Joëlle Quetin-Leclercq, Mansourou Moudachirou, Jacques Poupaert, Georges C. Accrombessi
Pages: 65-70
Antimicrobial, antioxidant and cytotoxic effects of methanolic extracts of leaves and stems of Glycosmis pentaphylla (Retz.)
Md. Amran Howlader, Farhana Rizwan, Shapna Sultana, Mohammad Rakibur Rahman, K. M. Shams-Ud-Doha, Rumana Mowla, Apurba Sarker Apu
Pages: 137-140
Assessment of antibacterial, thrombolytic and cytotoxic potential of Cassia alata seed oil
Adnan Mannan, Md. Junaate Kawser, A. M. Abu Ahmed, Nazneen Naher Islam, S. M. Murshidul Alam, Mohammad Asif Emran Khan Emon and Shipan Das Gupta
Pages: 56-59
Chemoprotective Potentials of Ocimum gratissimum in Diesel Petroleum induced Hepatotoxicity in Albino Wistar Rats
Ujowundu C.O., Nwokedinobi N., Kalu F.N., Nwaoguikpe R.N., Okechukwu R.I.
Pages: 56-61
Aqueous Extract of Combretum dolichopentalum Leaf - a Potent Inhibitor of Carbon Tetrachloride Induced Hepatotoxicity in Rats
Kalu F.N., Ogugua V.N., Ujowundu C.O., Nwaoguikpe R.N.
Pages: 114-117
Antimicrobial and Cytotoxic Activity of the Methanol Extract of Paederia foetida Linn. (Rubiaceae)
Helal Morshed, Md.Siddiqul Islam, Salma Parvin, Maizbha Uddin Ahmed, Mohammad Safiqul Islam, A. G. M. Mostofa, Muhammad Shahdaat Bin Sayeed
Pages: 77-80
The Antioxidative Potentials of Gongronema latifolium on Diesel Petroleum Induced Hepatotoxicity
Ujowundu C.O., Kalu F.N., Nwaoguikpe R.N., Okechukwu R. I. and Ihejirika C.E.
Pages: 90-94
Pharmacological Study of a Siddha Holistic Herb Sivakaranthai - Sphaeranthus Amaranthoides Burm for Analgesic and Anti-Inflammatory activities
V. Thanigavelan, V.Lakshmanakumar, V.Kaliyamurthi, M. Pitchiah Kumar, G. Victor Rajamanickam
Pages: 95-101
Toxicopathological overview of analgesic and anti-inflammatory drugs in animals
C. M. Modi, S.K. Mody, H.B. Patel, G.B. Dudhatra, Avinash Kumar, Madhavi Avale
Pages: 149-157
Antiviral Activity of Freshwater Algae
Sayda M. Abdo, Mona H. Hetta, Waleed M. El-Senousy, Rawheya A. Salah El Din, Gamila H. Ali
Pages: 21-25
In-Vitro Antioxidant and Cytotoxicity Screening of Different Bark Extracts of Aegle Marmelos L
Kaise Hamid, Farhana Diba, Kaniz Fatima Urmi, Muhammad Erfan Uddin, Fatema Tuz Zohera, Md. Razibul Habib
DOI: 10.7324/JAPS.2012.2315Pages: 92-95
Genotoxicity of anticancer drug Azathioprine (Imuran): role of Omega-3 (?-3) oil as protective agent
Elelaimy I.A, Elfiky S.A., Hassan A.M., Ibrahim H.M., Elsayad R.I.
DOI: 10.7324/JAPS.2012.2404Pages: 14-23
Isolation and Elucidation of Pyrrolizidine alkaloids from tuber of Gynura pseudo-china (L.) DC
Tri Windono, Umar A. Jenie, Leonardus B. S. Kardono
DOI: 10.7324/JAPS.2012.2509Pages: 05-09
Evaluation of Dimethylthiazol Diphenyl Tetrazolium Bromide and Propidium Iodide Inclusion Assays for the Evaluation of Cell Viability by Flow Cytometry
Nabil Ben Salem Abid, Zyed Rouis, Faten Nefzi, Nidhal Souelah, Mahjoub Aouni
DOI: 10.7324/JAPS.2012.2525Pages: 10-14
Effect of leave extract of Ocimum basilicum on deltamethrin induced nephrotoxicity and oxidative stress in albino rats
Saber A. Sakr, Wael M. Al-Amoudi
DOI: 10.7324/JAPS.2012.2507Pages: 22-27
Drug-Induced Hepatotoxicity: A Review
Aashish Pandit, Tarun Sachdeva, Pallavi Bafna
DOI: 10.7324/JAPS.2012.2541Pages: 233-243
Management of Changes in Liver Chemistry in Male Rats Acutely Exposed to Crude Petroleum Oil
C.O. Ujowundu, F.N. Kalu, L.A. Nwaogu, E.U. Ezeji, K.O. Igwe
DOI: 10.7324/JAPS.2012.2604Pages: 116-120
Antimicrobial, cytotoxic and thrombolytic activityof Cassia senna leaves (family: Fabaceae)
Md. Kamal Hossain, Md. Musfizur Hassan, Most. Nazma Parvin, Md. Mahmudul Hasan, Md. Siddiqul Islam, Md. Ahsanul Haque
DOI: 10.7324/JAPS.2012.2607Pages: 186-190
Supporting the immune system through functional modulation of carbon tetrachloride intoxicated splenic macrophages by administering Tinospora cordifolia
Biswajit Chakraborty, Mahuya Sengupta
DOI: 10.7324/JAPS.2012.2715Pages: 117-124
Thrombolytic Activity and Preliminary Cytotoxicity of Five Different Fractions of Methanol Extract of Allamanda cathartica Leaf
Rehan Sarker, Tasnuva Sharmin, Sharmin Reza Chowdhury, Farhana Islam
DOI: 10.7324/JAPS.2012.2717Pages: 129-132
Cytotoxicity Activity and Phytochemical Screening of Cochlospermum tinctorium Perr Ex A. Rich Rhizome
Akpemi Audu Musa
DOI: 10.7324/JAPS.2012.2723Pages: 155-159
Anti-Influenza Virus Activities of Commercial Oregano oils and their Carriers
Selvarani Vimalanathan, James Hudson
DOI: 10.7324/JAPS.2012.2734Pages: 214-218
Subtherapeutic Dose of Prazosincan Ameliorate Metformin Induced Lactic Acidosis in Renal Compromised Rats
Quazi Shahir Ahmed, Kauser Sayedda
DOI: 10.7324/JAPS.2012.2741Pages: 246-248
Protective effect of regular aerobic training on inflammatory and toxicity markers of lung tissue in L-NAME-induced hypertension
Roghoye Heidarzadeh, Valiollah Dabidi Roshan , Javad Ashrafi
DOI: 10.7324/JAPS.2012.2810Pages: 68-73
Design and evaluation of liposomal delivery system for L-Asparaginese
Anindita De, D. Nagaswamy Venkatesh
DOI: 10.7324/JAPS.2012.2818Pages: 112-117
Estrogenic activity of Citrus medica L. leaves growing in Egypt
Taha S. El-Alfy, Mona H. Hetta, Nemat Z. Yassin, Rehab F. Abdel Rahman, Esraa M. Kadry
DOI: 10.7324/JAPS.2012.2831Pages: 180-185
Study of Media Effect toward Antimicrobial, Antiplasmodial, Herbicidal Activities and Toxicity of Extract Produced by Acropora dibranchiata-Associated Moraxella Sp. RA15
Risa Nofiani, Rizmahardian Ashari Kurniawan, Tika Mabella, Puji Ardiningsih, Titin Anita Zahara and Sunarto
DOI: 10.7324/JAPS.2012.2902Pages: 010-014
Effects of Rosiglitazone and Acarbose (with and without Cornstarch Diet) on Serum Electrolytes in Diabetic Rats
Humera Khatoonand Rahila Najam
DOI: 10.7324/JAPS.2012.2910Pages: 050-053
Isolation of a novel triterpene from the Essential oil of fresh leaves of Chromolaena odorata and its in-vitro cytotoxic activity against HepG2 cancer cell line
Velliangiri Prabhu and Subban Ravi
DOI: 10.7324/JAPS.2012.2926Pages: 132-136
Kalanchoe thrysiflora Harv. and Kalanchoe marmorata Baker, DNA Profiling, biological guided fractionation of different extracts, isolation and identification of cytotoxic compounds
Abdel Nasser Singab, Sherweit El-Ahmady, Rola Milad, Sally Saad
DOI: 10.7324/JAPS.2012.2838Pages: 215-220
Phytochemical screening, cytotoxicity and anti-inflammatory activities of the Zimbabwean endemic plant Phyllanthus serpentinicola Radcl.-Sm. (Phyllanthaceae)
C. Zimudzi, L.F.Gwenhure, N.Kunonga, S. Kativu and J. Jere
DOI: 10.7324/JAPS.2012.21010Pages: 050-053
In vitro Evaluation of Antimicrobial and Cytotoxic Activities of Rosmarinus officinalis L. (Lamiaceae) Essential Oil Cultivated from South-West Tunisia
Ines Ben Chobba, Ahmed Bekir, Riadh Ben Mansour, Noureddine Drira, Néji Gharsallah and Adel Kadri
DOI: 10.7324/JAPS.2012.21107Pages: 034-039
Comparative Anti-microbial activity and brine shrimp lethality bioassay of different parts of the plant Moringa oleifera lam
Kaniz Fatima Urmi, Nurul Huda Md. Masum, Abu Hasanat Md. Zulfiker, Md. Kamal Hossain and Kaiser Hamid
DOI: 10.7324/JAPS.2012.21216Pages: 085-088
Strategies to evaluate antioxidant and cytotoxic activity of pet ether extract of Artocarpus chama Buch. seed
Taksim Ahmed, Mohammad Nasir Uddin, Md. Kamal Hossain, Md. Imamul Islam, Nizam Uddin, Md. Ehsanul Haque Mazumder
DOI: 10.7324/JAPS.2012.21217Pages: 089-095
Adverse Cutaneous Drug Reactions in a Tertiary Care Center Patients: a Prospective Analysis
Sandeep Mahapatra and Umashanker Pd Keshri
DOI: 10.7324/JAPS.2012.21218Pages: 096-098
Acute Toxicity and in-vivo Effects of Leaf Extracts of Byrsocarpus Coccineus Shum & Thonn in Pregnant Rat Uterus
Wazis CH, Anuka JA, Timothy SY, Zezi AU, Mohammed GT, Hussaini IM
DOI: 10.7324/JAPS.2012.21224Pages: 130-136
Toxicological Evaluation of Five Herbal Drugs Hawked In Minna, Niger State
Kelechi E. Okunji, Musa Galadima and Ali A. Jigam
DOI: 10.7324/JAPS.2012.21229Pages: 167-171
Evaluation of anti-diarrheal and anti-diabetic activities of the stem, barks and leaves of the plant Vernonia cinerea (Family: Asteraceae)
Md. Ahsanul Haque, Chowdhury Sayef Abdullah, Bilquis Romana, Md. Bodruddoza Rafique, Gazi Md. Zia-ulHuda, Sarder Fahim Hossain, Bilkis Begum
DOI: 10.7324/JAPS.2013.30113Pages: 069-072
Protective Effect of Adiantum Capillus Against Chemically Induced Oxidative Stress by Cisplatin
Kanchan Gaikwad, Swati Dhande, Y M Joshi, Vilasrao Kadam
DOI: 10.7324/JAPS.2013.30211Pages: 065-068
Modulatory effect of Allium sativum Ethanolic Extract on Cultured Human Lymphocytes
Sukanya Shetty, Shama Rao, SuchethaKumari N, Madhu L N, Vishakh R
DOI: 10.7324/JAPS.2013.3413Pages: 073-077
Analysis of Some Selected Toxic Heavy Metals in Some Branded Nigerian Herbal Products
Ekeanyanwu R.C., Njoku J.O., Nwodu P.O., Njokuobi A.E
DOI: 10.7324/JAPS.2013.3416Pages: 088-091
Hepatoprotective Effects of Ageratum conyzoides L. on Biochemical Indices Induced by Acetaminophen Toxicity in Wistar rats
Pawan K Verma, M Sultana, R Raina, S Prawez, S Pandita, Neha Jamwal and Arshad H Mir
DOI: 10.7324/JAPS.2013.34.S4Pages: S23-S27
Management of Benzodiazepine Dependence and Toxicity
Mohammad Shohel, Shoaib-Ul-Islam, Rasiqh Wadud, Zaki Farhad Habib, Farjana Malik, Sanjana Kabir and Hasan Mahmud Reza
DOI: 10.7324/JAPS.2013.3624Pages: 146-151
Antiretroviral Therapy Regimen Change Among HIV/AIDS Patients in Nekemt Hospital: a Primary Care Hospital in Oromia Regional State, Ethiopia
Meseret Wube, Andualem Tesfaye, Segewkal Hawaze
DOI: 10.7324/JAPS.2013.3807Pages: 036-040
A case report of a bipolar disorder patient with severe lithium poisoning possibly induced by interaction between risperidone, telmisartan, fluvoxamine and lithium
Yi Xin Chengand Chee Ping Chong
DOI: 10.7324/JAPS.2013.38.S13Pages: S79-S82
Herbal Hepatotoxicity: A Review on Phytochemical Induced Liver Injury
Prasad G. Jamkhande, Ganesh S. Tolsarwad, Priti S. Tidke
DOI: 10.7324/JAPS.2013.38.S16Pages: S106-S110
Effect of Artemisinin-Based Combination Therapy on some Selected Liver Function Indices of Pregnant Wistar Albino Rats
Ugian E.A, Dasofunjo K, Nwangwa J.N, Asuk A.A, Akam M.S, Ajing E.N, Ugoanyanwu F.U.
DOI: 10.7324/JAPS.2013.3926Pages: 152-154
Comparative evaluation of the analgesic activity of several populations of Tunisian Citrullus colocynthis Schrad. immature fruits
Belsem Marzouka, Ehsen Haloui, Nadia Fenina, Mahjoub Aouni, Zohra Marzouk
DOI: 10.7324/JAPS.2013.31028Pages: 156-160
Evaluation of Herbalife Nutritional Supplements in the Hepatic Function of Rats
Davi Feder, Marcelo Rodrigues Bacci, Janaina Aparecida Boide Santos, Marília Tavares Campos de Oliveira Gaboardi, Carolina Stangenhaus, Juliana Klein Lewi, Marina Akiko Rampazzo Del Valle Shiroma, Paulo Emanuel Barbosa dos Santos Junqueira, Giuliana Petri, Fernando Luiz Affonso Fonseca
DOI: 10.7324/JAPS.2013.31030Pages: 167-169
Antimicrobial, Genotoxic and Acute Toxic Effects of Newly Synthesized N-Pyridine Schiff Base Derivatives
Buket Kunduhoglu, Sevil Pilatin, Emre Ceyhan, Hakan Dal
DOI: 10.7324/JAPS.2013.31102Pages: 005-010
Acute and subacute oral toxicity evaluation of benincasa hispida extract in rodents
Patel RK, Patel SB, Shah JG
DOI: 10.7324/JAPS.2012.2842Pages: 250-253
Xylopioxyde and other bioactive kaurane-diterpenes from Xylopia aethiopica Dunal (Annonaceae)
Désiré SOH, Ernestine NKWENGOUA, Igor NGANTCHOU, Barthélemy NYASSE, Colette DENIER, Véronique HANNAERT, Kamel H. SHAKER and Bernd SCHNEIDER
DOI: 10.7324/JAPS.2013.31203Pages: 013-019
Cytotoxic effects of antiglypican-3 against HepG2 cell line
Randa A Zaghloul, Mohammed M H Al-Gayyar, Mamdouh M El-Shishtawy, Mohamed A. Ebrahim
DOI: 10.7324/JAPS.2013.31206Pages: 031-035
Toxicological Evaluation of Aqueous Leaf Extract of Chromolaena Odorata in Male Wistar Albino Rats
Asomugha RN, Okafor PN, Ijeh II, Orisakwe OE, Asomugha AL, Ndefo JC
DOI: 10.7324/JAPS.2013.31216Pages: 089-092
Antituberculotic Chemotherapy-General and Hepatic Toxicity Revisited
Ali Akbar Sial, Aisha Jabeen, Talha bin Fayyaz, Maria Muneer, Rabia Bushra, Nusrat Bano, Mirza Tasawer Baig
DOI: 10.7324/JAPS.2014.40124Pages: 148-152
Development of sensitive molecular markers for detecting the genotoxicity induced by two pyrethroids insecticides, Cypermethrin and permethrin, to the Meditnerranean sole, Solea senegalensis (Kaup 1858)
brahim El-Elaimy, Mohamed Fathy Farag Bayomy, Asmaa Galal-Khallaf, Khaled Mohammed-Geba, G. Martínez-Rodríguez, J.M. Mancera
DOI: 10.7324/JAPS.2014.40206Pages: 034-042
In vitro evaluation of antimicrobial, cytotoxic and antioxidant activities of Crude methanolic extract and other fractions of Sterculia villosa barks
Syed Sami-ul Haque, Md. Mamun Or Rashid, Md. Akhtaruzzaman Prodhan, Sadia Noor, Atanu Das
DOI: 10.7324/JAPS.2014.40308Pages: 035-040
Cytotoxicity assessment of aqueous extract from root barks of Calotropis procera (Ait.) R. Br. in human intestinal Caco-2 and mouse neuroblastoma Neuro-2a cell lines
Geoffroy G. Ouedraogo, Serge Moukha, Théophile A. Mobio, Moustapha Ouedraogo, Pierre I. Guissou and Edmond E. Creppy
DOI: 10.7324/JAPS.2014.40401Pages: 001-007
Evaluation of acute and sub-chronic toxicities of Vensestin Cleansers: a polyherbal supplement in female Wistar Albino rats
Kingsley C. Patrick-Iwuanyanwu, Edidiong A. Okon and Orish Ebere Orisakwe
DOI: 10.7324/JAPS.2014.40611Pages: 074-078
Cytotoxic activity and apoptosis induction of 8-hydroxyisocapnolactone-2, 3-diol and its combination with Doxorubicin on MCF-7 and T47D cells
Ratna Asmah Susidarti, Riris Istighfari Jenie, Muthi Ikawati, Dyaningtyas Dewi Pamungkas Putri, Edy Meiyanto
DOI: 10.7324/JAPS.2014.40614Pages: 089-097
The effects of Hydnophytum formicarum ethanolic extract towards lymphocyte, vero and T47d cells proliferation in vitro
David Darwis, Triana Hertiani, Ediati Samito
DOI: 10.7324/JAPS.2014.40616Pages: 103-109
Anticancer activities of mushroom polysaccharides on chemically-induced colorectal cancer in rats
Sorial A. Moharib, Nabila Abd El Maksoud, Halla M. Ragab and Mahmoud, M. Shehata
DOI: 10.7324/JAPS.2014.40710Pages: 054-063
Assessment of cytotoxic activities of Phyllanthus amarus and Monstera deliciosa
Dilshad Noor Lira, Md. Aftab Uddin, Mohi Uddin, Abu Shara Shamsur Rouf
DOI: 10.7324/JAPS.2014.40719Pages: 110-113
Evaluation of in-vitro apoptosis induction, cytotoxic activity of Hymenodictyon excelsum (Roxb) Wall in Dalton’s lymphoma ascites (DLA) and Lung fibroblast - Mouse L929 cell lines
Kalathil Khairunnisa and Dhananjayan Karthik
DOI: 10.7324/JAPS.2014.40803Pages: 011-017
Chronic LD50 vs safest dose for the methanolic extract of curry leaves (Murraya koenigii) cultivated in Malaysia
Marwan Saad Azzubaidi, Anil Kumar Saxena, Ahmed Ghazi Alattraqchi and Abualrahman Mohammed Abdualkader
DOI: 10.7324/JAPS.2014.40811Pages: 056-058
In vitro cytotoxic effect of Cleistanthus collinus extracts and fractions on mouse cell line
Thamburaj Suman, Ramaraj Elangomathavan, Soundherrajan Ilavenil and Samiraj Ramesh
DOI: 10.7324/JAPS.2014.401008Pages: 044-046
Antimicrobial and Cytotoxic Activities of Endophytic Fungi Isolated from Artemisia annua L
Puji Astuti, Wahyono, Titik Nuryastuti, Indah Purwantini, Purwanto
DOI: 10.7324/JAPS.2014.401009Pages: 047-050
Acute Toxicity and Suppressive Effects of a Curcumin Analogue Gamavuton-0 (Gvt-0) On CFA-Induced Arthritis in rats
Zullies Ikawati, Nunung Yuniarti, Supardjan Amir Margono
DOI: 10.7324/JAPS.2014.4114Pages: 019-023
Safety evaluation of polyherbal Unani formulation -Deedan in Wistar rats
Khalid Ghazanfar, Showkat A. Dar, Tazeen Nazir, Irfat Ara, Akbar Masood, Seema Akbar
DOI: 10.7324/JAPS.2015.50116Pages: 089-093
Piceatanol: Anti-Cancer Compound From Gewang Seed Extract
Leny Heliawati, Agus Kardinan, Tri Mayanti, Roekmi-ati Tjokronegoro
DOI: 10.7324/JAPS.2015.50119Pages: 110-113
Occurrence, harmful effects and analytical determination of Ochratoxin A in coffee
Abdulmumin A Nuhu
DOI: 10.7324/JAPS.2015.50121Pages: 120-127
Cytotoxic compounds from the leaves of Garcinia cowa Roxb.
Fatma Sri Wahyuni, Khozirah Shaari, Johnson Stanslas, Nordin Lajis, Dachriyanus Hamidi
DOI: 10.7324/JAPS.2015.50202Pages: 006-011
Acute Oral Toxicity of Immunoglobulin Y (IgY) anti HIV in Mice
Sri Agus Sudjarwo, Wiwiek Indriyani, Nasronudin Nasronudin, Giftania Wardani Sudjarwo, Koerniasari Koerniasari
DOI: 10.7324/JAPS.2015.50218Pages: 123-126
Antimicrobial and cytotoxic acetogenin from Polyalthia debilis
Somchai Boonpangrak, Rungrot Cherdtrakulkiat, Ratchanok Pingaew, Patumporn Manam, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul
DOI: 10.7324/JAPS.2015.50303Pages: 013-018
Bioactive triterpenoids, antimicrobial, antioxidant and cytotoxic activities of Eclipta prostrata Linn.
Rungrot Cherdtrakulkiat, Somchai Boonpangrak, Ratchanok Pingaew, Supaluk Prachayasittikul, Somsak Ruchirawat, Virapong Prachayasittikul
DOI: 10.7324/JAPS.2015.50308Pages: 046-050
Evaluation of the cytotoxic activity of extracts from medicinal plants used for the treatment of malaria in Kagera and Lindi regions, Tanzania
Ramadhani S. O. Nondo, Mainen J. Moshi, Paul Erasto, Denis Zofou, Abdel J. Njouendou, Samuel Wanji, Moses N. Ngemenya, Abdul W Kidukuli, Pax J. Masimba, Vincent P.K. Titanji
DOI: 10.7324/JAPS.2015.50402Pages: 007-012
Acute and Sub-acute oral toxicity studies of Deedan-A Unani drug in Albino rats
Showkat A. Dar, Khalid Ghazanfar, Seema Akbar, Akbar Masood, Tazeen Nazir, Khalid M. Siddiqui, Pawan Kumar
DOI: 10.7324/JAPS.2015.50418Pages: 107-114
In vitro Cytotoxic Activity of New Triphenyltin (IV) Alkyl-isopropyl-di-thiocarbamate Compounds on Human Acute T-Lymphoblastic Cell Line
Normah Awang, Nor Syaidatul Akmal Mohd Yousof, Nor Fadilah Rajab, Nurul Farahana Kamaludin
DOI: 10.7324/JAPS.2015.54.S2Pages: 007-011
Environmental biotoxicity screening of some pyrrole and 1,4-dihydropyridine heterocyclic derivatives
A. Idhayadhulla, Aseer Manilal, Behailu Merdekios and R. Surendra Kumar
DOI: 10.7324/JAPS.2015.50519Pages: 101-105
Antibacterial, antitussive, antioxidant and toxicological evaluation of Joshanda lozenges
Monika Bansal, Monica Gulati, Sachin Kumar Singh, Sanjiv Duggal
DOI: 10.7324/JAPS.2015.50711Pages: 064-070
Antimicrobial activity of compounds from Acanthospermum hispidum DC and Caesalpinia bonduc (L.) ROXB: Beninese plants used by healers against HIV-associated microbial infections
Alban G. Houngbèmè, Habib M.Y.Ganfon, Sédami Medegan, Boniface Yèhouénou, Bouraïma Bambola, Clément Gandonou, Fernand A. Gbaguidi
DOI: 10.7324/JAPS.2015.50812Pages: 073-081
Hepatotoxicity following separate administration of two phosphodiesterase-5 inhibitors (sildenafil & tadalafil) and opioid (tramadol); evaluation of possible reversal following their withdrawal
Victor U. Nna, Ubom P. Akpan, Victoria E. Okon, Item J. Atangwho
DOI: 10.7324/JAPS.2015.50817Pages: 105-113
Toxicological Investigation of Ethanolic Extract of Epipremnum aureum in Rodents
Sreemoy Kanti Das, Pinaki Sengupta, Mohd. Shahimi Mustapha, Arindam das, Md. Moklesur Rahman Sarker, Muhammad Kifayatullah
DOI: 10.7324/JAPS.2015.58.S9Pages: 057-061
Evaluation of acute and chronic toxic effects of Algerian germander in Swiss albino mice
Imane KRACHE, Naouel BOUSSOUALIM, Noureddine CHAREF, Hayat TRABSA, Soraya OUHIDA, Faycel BENBACHA, Zahret El Youm DAAMOUCHE, Nadia BENZIDANE, Abderrahmane BAGHIANI, Seddik KHENNOUF, Lekhmici ARRAR
DOI: 10.7324/JAPS.2015.510.S5Pages: 027-032
Cytotoxic Triterpenes and Sterols from Pipturus arborescens (Link) C.B. Rob.
Mariquit M. De Los Reyes, Glenn G. Oyong, Virgilio D. Ebajo Jr., Vincent Antonio S. Ng, Chien-Chang Shen, Consolacion Y. Ragasa
DOI: 10.7324/JAPS.2015.501104Pages: 023-030
Synthesis of barbituric acid derivatives using microwave irradiation method and in vitro evaluation of antimicrobial and cytotoxic activity
M. A. Sattar, Mst. Khodeza Khatun, Rafiquel Islam, Md. Hossain Sohrab, Sharif M. Al-Reza
DOI: 10.7324/JAPS.2015.501106Pages: 038-042
In vitro Cytotoxicity and Glucose Uptake Activity of Fruits of Terminalia bellirica in Vero, L-6 and 3T3 cell lines
Mary Shoba Das, Gayathri Devi
DOI: 10.7324/JAPS.2015.501215Pages: 092-095
Cytotoxic and Antibacterial Evaluation of Coumarins and Chromanone Acid from Calophyllum symingtonianum
Nurul Iman Aminudin, Farediah Ahmad, Muhammad Taher, Razauden Mohamed Zulkifli
DOI: 10.7324/JAPS.2016.600104Pages: 023-027
A comparative study of the effect of amikacin administered through autoinjector and manual injection on biochemical parameters in rats
Anitha Roy, R. Vijayaraghavan, R. V. Geetha, Anitha Magesh, S. Vishnu Priya, Anusha Ramasamy, U Vidyalakshimi, K RaagaNamrata, S. Krishna Mohan, Madhan Chakkaravarthy
DOI: 10.7324/JAPS.2016.60216Pages: 109-114
Prophylactic effects of thymoquinone against carbon tetrachloride-induced hepatic damage in Sprague-Dawley rats
Khaled M. A. Hassanein, Ahmed Al-Emam, Khaled Radad
DOI: 10.7324/JAPS.2016.60226Pages: 167-171
Repeated toxicological study and cardiotoxicity of hydroalcoholic root extract of Paullinia pinnata L (Sapindaceae)
Eliassou Mariame, Diallo Aboudoulatif, Lawson Evi Povi, Adi Kodjo, Metowogo Kossi, Padaro Essohana, Kwashie Eklu-Gadegkeku, Edmond Creppy
DOI: 10.7324/JAPS.2016.60304Pages: 024-028
Toxicological Study of a Siddha Sastric Formulation Arumuga Chendhuram in Rat Model
Ramamurthy Murugan, Thanigavelan Vembu, Manickavasakam Kumarswamy
DOI: 10.7324/JAPS.2016.60314Pages: 081-087
Chemical constituents and cytotoxic effect from the barks of Goniothalamus chinensis Merr. & Chun. growing in Vietnam
Loi Vu Duc, Tung Bui Thanh, Hai Nguyen Thanh, Vung Nguyen Tien
DOI: 10.7324/JAPS.2016.60401Pages: 001-005
Evaluation of In vitro Antioxidant and In vivo Pharmacological Activity of Leaf Extracts of Hoya parasitica (Wall.)
Ummee Habiba Tania, Md Rajib Hassan, Nusrat Jahan Eshita, Rumana Akhter, Mohammad Shahriar
DOI: 10.7324/JAPS.2016.60526Pages: 163-170
In vitro antioxidant and cytotoxic activity of Zanthonitrile isolated from Zanthoxylum alatum
Indrajit Karmakar, Sagnik Haldar, Mainak Chakraborty, Saikat Dewanjee, Pallab Kanti Haldar
DOI: 10.7324/JAPS.2016.60621Pages: 119-122
Ameliorative potential of Aframomum melegueta extract in cadmium-induced hepatic damage and oxidative stress in male Wistar rats
Babatunji Emmanuel Oyinloye, Basiru Olaitan Ajiboye, Oluwafemi Adeleke Ojo, Habiba M. Musa, Sunday Amos Onikanni, Abiodun Ayodele Ojo
DOI: 10.7324/JAPS.2016.60714Pages: 094-099
Amelioration of the nephrotoxic effect of potassium dichromate by whey protein and/or Nigella sativa oil in male albino rats
Samir A. E. Bashandy, Mohamed M. Amin, Fatma A. Morsy, Salma A. El-Marasy
DOI: 10.7324/JAPS.2016.60807Pages: 044-050
Efficacy and In Vitro Cytotoxicity of Nanostructured Lipid Carriers for Paclitaxel Delivery
Shady Ali Swidan, Hassan Mahmoud Ghonaim, Ahmed Mahmoud Samy, Mamdouh Mostafa Ghorab
DOI: 10.7324/JAPS.2016.60903Pages: 018-026
Acute and Subchronic Toxicities of Indonesian Mistletoes Dendrophthoe pentandra L. (Miq.) Ethanol Extract
Resmi Mustarichie, Sohadi Warya, Nyi Mekar Saptarini, Ida Musfiroh
DOI: 10.7324/JAPS.2016.60916Pages: 109-114
Preclinical safety assessment of glycosides based standardized fenugreek seeds extract: Acute, subchronic toxicity and mutagenicity studies
Pallavi Deshpande, Vishwaraman Mohan, Prasad Thakurdesai
DOI: 10.7324/JAPS.2016.60927Pages: 179-188
Evaluation of Crataeva nurvala extracts as antioxidant, antiproteolytic and cytotoxic against hepato-carcinoma and mouse melanoma cell lines
Swati N. Hade, Prachi A. Joshi, Harshda H. Pilley, Varsha P. Wadegaonkar, Prasad A. Wadegaonkar
DOI: 10.7324/JAPS.2016.60928Pages: 189-196
Protective Effects of Solanum erianthum D. Don Leaf Extract on Lead-Induced Toxicity in Adult Wistar Rats
Olusegun Babalola, John Agbi, Adeleke Badiora, Oladayo Areola
DOI: 10.7324/JAPS.2016.601016Pages: 113-123
Styrax camporum and S. ferrugineus fruits: norneolignans, antioxidant and cytotoxic activities
Thais de Almeida Silva, Evelise Martins Polo, Camila Yamasita Henrique, Osvaine Júnior Alvarenga Alves, Heloiza Diniz Nicolella, Valéria Maria Melleiro Gimenez et al.
DOI: 10.7324/JAPS.2016.601112Pages: 075-080
Extracts of Codiaeum variegatum (L.) A. Juss is Cytotoxic on Human Leukemic, Breast and Prostate Cancer Cell Lines
Mathias Tawiah Anim, Christopher Larbie, Regina Appiah-Opong, Isaac Tuffour, Kofi Baffour-Awuah Owusu, Abigail Aning
DOI: 10.7324/JAPS.2016.601114Pages: 087-093
Sub-chronic oral toxicity study of Kushta Hajrul-Yahood (A Herbo-mineral Unani formulation) in Wistar rats
Showkat A. Dar, Seema Akbar, Khalid Ghazanfar, Mariya Hamdani, Tazeen Nazir, Masood S Mir, Akbar Masood, Humma Rafiq, Showkat A Ganie
DOI: 10.7324/JAPS.2016.601117Pages: 105-113
Biological capacity and chemical composition of secondary metabolites from representatives Japanese Lichens
Eman F. Ahmed, Waill A. Elkhateeb, Hanan A. A. Taie, Mostafa E. Rateb, Walid Fayad
DOI: 10.7324/JAPS.2017.70113Pages: 098-103
Inhibition of CYP2S1 mediated metabolism of anticancer prodrug AQ4N by liarozole
Naveen K. M. Singh, Shawn R. White, Sudhakar Kalagara3, Samuel Kadavakollu
DOI: 10.7324/JAPS.2017.70201Pages: 001-007
Synthesis and molecular docking of novel non-cytotoxic anti-angiogenic sulfonyl coumarin derivatives against hepatocellular carcinoma cells in vitro
Eslam R. El- Sawy, Manal Sh Ebaid, Hanaa M. Rady, Aziza B. Shalby, Khadiga M. Ahmed, Heba M. Abo-Salem
DOI: 10.7324/JAPS.2017.70207Pages: 049-066
Toxicity of four novel Polyhedral Oligomeric Silsesquioxane (POSS) particles used in anti-cancer drug delivery
Abdulmajeed Almutary, Barbara Sanderson
DOI: 10.7324/JAPS.2017.70212Pages: 101-105
Evaluation of the cytotoxic activity of extracts from six species of Phlomis genus
Parisa Sarkhail, Shamim Sahranavard, Marjan Nikan, Saeedeh Gafari, Bahara Eslami-Tehrani
DOI: 10.7324/JAPS.2017.70225Pages: 180-184
Toxicological studies and assessment of pharmacological activities of Abrus precatorius L. (Fabaceae) ethanolic leaves extract in the management of pain, psychiatric and neurological conditions: An in-vivo study
Sumanta Mondal, Debjit Ghosh, Krishna Chaitanya Anusuri, Seru Ganapaty
DOI: 10.7324/JAPS.2017.70229Pages: 207-216
Cytotoxic and antioxidant capacity of extracts from Vaccinium meridionale Swartz (Ericaceae) in transformed leukemic cell lines
Margarita González, Ismael Samudio, Luis Gonzalo Sequeda-Castañeda, Crispín Celis, José Iglesias, Ludis Morales
DOI: 10.7324/JAPS.2017.70305Pages: 024-030
Median lethal dose (LD50) and cytotoxicity of Adriamycin in female albino mice
Rehab M. Mosaad, Amany Samir, Hassan M. Ibrahim
DOI: 10.7324/JAPS.2017.70312Pages: 077-080
Acute and sub-acute toxicity of Harungana madagascariensis LAM (Hypericaceae) stem bark methanol extract
Rebecca Madeleine Ebelle Etame, Raymond Simplice Mouokeu, Rosalie Anne Ngono Ngane, Jean Paul Assam Assam, Azaber Mamoune Masoohe, Raphael Tientcheu, Mylene Laure Hopogap, François Xavier Etoa
DOI: 10.7324/JAPS.2017.70326Pages: 160-167
In Vitro Cytotoxic Activity of Laurencia papillosa, Marine Red Algae from the Lebanese Coast
Mona Y. Tannoury, Antoine M. Saab, Josiane M. Elia, Nafez N. Harb, Hassane Y. Makhlouf, Mona Diab-Assaf
DOI: 10.7324/JAPS.2017.70328Pages: 175-179
Seasonal Toxicity Assessment of Oblong Blowfish (Takifugu oblongus) from Tamil Nadu Coast, India
S. M. Indumathi, Samanta Sekhar Khora
DOI: 10.7324/JAPS.2017.70330Pages: 188-193
Identification, Biodegradation and bio-evaluation of biopolymer produced from Bacillus thuringenesis
Mostafa Abd El-Hameed El-Abd, Hussein Hosny El-Sheikh, Saeid Desouky, Amr Shehab
DOI: 10.7324/JAPS.2017.70414Pages: 103-110
Nutritional effects, toxicity and haematology studies of the ethanolic root bark extract of Hymenocardia acida Tul (Euphorbiaceae)
Paul N. Olotu, Ijeoma A. Olotu, Mighi B. Kambasha, Abubakar Ahmed, Ukpe Ajima, Temitayo L. Ohemu, Victoria A. Okwori, Dalen G. Dafam, Francis M. Agwom, Jane David, Emmanuel U. Onche
DOI: 10.7324/JAPS.2017.70415Pages: 111-114
HAART and Hepatotoxicity
Devaraj Ezhilarasan, Mohan Srilekha, Ramanathan Raghu
DOI: 10.7324/JAPS.2017.70433Pages: 220-226
The natural anti-tubercular agents: In silico study of physicochemical, pharmacokinetic and toxicological properties
Mohammad Firoz Khan, Md. Abdul Bari, Md. Kamrul Islam, Md. Shariful Islam, Md. Shahidulla Kayser, Nusrat Nahar, Md. Al Faruk, Mohammad A. Rashid
DOI: 10.7324/JAPS.2017.70506Pages: 034-038
Biological Activities of Plants used in Egyptian Ethnopharmacology
Khaled Rashed, Maria Carmo Barreto
DOI: 10.7324/JAPS.2017.70508Pages: 046-050
Screening of in vitro cytotoxic activity of brown seaweeds against hepatocellular carcinoma
Suja Gunasekaran, Vinoth Kumar Thirumalairaj, Lakshmana Senthil Shanmugasokan, Suganya Pitchai, Rincy Yesudas, Amrutha Chacko
DOI: 10.7324/JAPS.2017.70509Pages: 051-055
Antibacterial and cytotoxic activities screening of symbiotic fungi extract isolated from marine sponge Neopetrosia chaliniformis AR-01
Dian Handayani, Muh. Ade Artasasta
DOI: 10.7324/JAPS.2017.70512Pages: 066-069
Anti-oxidative and cytotoxic attributes of phenolic rich ethanol extract of Musa balbisiana Colla inflorescence
Vageesh Revadigar, Majed Ahmed Al-Mansoub, Muhammad Asif, Mohammad Razak Hamdan, Amin Malik Shah Abdul Majid, Mohd Zaini Asmawi, Vikneswaran Murugaiyah
DOI: 10.7324/JAPS.2017.70518Pages: 103-110
In vitro cytotoxicity analysis of sulfated polysaccharides from green seaweed Codium tomentosum Stackhouse, 1797
Pagolu Navya, Samantha Sekar Khora
DOI: 10.7324/JAPS.2017.70605Pages: 033-036
Leaves and seeds of Syzygium cumini extracts produce significant attenuation of 2,2 azobis-2-amidinopropane dihydrochloride-induced toxicity via modulation of ectoenzymes and antioxidant activities
Raphaela M. Borges, Paula E. R. Bitencourt, Carolina S. Stein, Guilherme V. Bochi, Aline Boligon, Rafael Noal Moresco, Maria Beatriz Moretto
DOI: 10.7324/JAPS.2017.70606Pages: 037-048
In vitro antioxidant, antimicrobial and cytotoxic activities and green biosynthesis of silver & gold nanoparticles using Callistemon citrinus leaf extract
Amal M. Saad, Abdel-Aleem H. Abdel-Aleem, Mosad A. Ghareeb, Manal M. Hamed, Mohamed S. Abdel-Aziz, Asmaa H. Hadad
DOI: 10.7324/JAPS.2017.70620Pages: 141-149
Behavioral profile and gastrointestinal evaluation of the hydro-alcoholic extract of Sida rhombifolia L. (typychá hû) in mice
O. Y. Heinichen, M. C. Hellión-Ibarrola, Y. Montalbetti, A. M. Velázquez, J. H. Dölz-Vargas2 , D. A. Ibarrola
DOI: 10.7324/JAPS.2017.70703Pages: 021-029
Comparative Study of Genotoxicity of Silver and Gold Nanoparticles Prepared by the Electric Spark Dispersion Method
Evgenii Plotnikov, Sergey Zhuravkov1, Andrew Gapeyev, Vladimir Plotnikov, Irina Martemianova, Dmitrii Martemianov1
DOI: 10.7324/JAPS.2017.70705Pages: 035-039
Papaya fruits extracts enhance the antioxidant capacity and modulate the genotoxicity and oxidative stress in the kidney of rats fed ochratoxin A-contaminated diet
Aziza A. El-Nekeety, Khaled G. Abdel-Wahhab, Sekena H. Abdel-Aziem, Fathia A. Mannaa, Nabila S. Hassan, Mosaad A. Abdel-Wahhab
DOI: 10.7324/JAPS.2017.70718Pages: 111-121
Oil of Mesua ferrea L. Seed as a Promising Pharmaceutical Excipient in Lipid Based Nanoformulation
Tapash Chakraborty, Malay K. Das
DOI: 10.7324/JAPS.2017.70721Pages: 133-141
Cytotoxicity Evaluation of Methanol Extracts of Some Medicinal Plants on P19 Embryonal Carcinoma Cells
Sara Soltanian, Mahboubeh Sheikhbahaei, Neda Mohamadi
DOI: 10.7324/JAPS.2017.70722Pages: 142-149
Counteraction of adriamycin-induced alterations in cardiac enzymes by Thespesia populnea leaf extract
Sangeetha Lakshmi A. Rajbanshi, Archana N. Paranjape, Vasu Appanna
DOI: 10.7324/JAPS.2017.70723Pages: 150-157
Synthesis, Characterization and Anticonvulsant Activity of Some Novel 4, 5-Disubstituted-1, 2, 4-Triazole Derivatives
Yasmin Khatoon, Mohammad Shaquiquzzaman, Vijender Singh, Mohammad Sarafroz
DOI: 10.7324/JAPS.2017.70724Pages: 158-167
Preliminary safety assessment of Eudragit® polymers nanoparticles administration in the rat brain
Mosaad A. Abdel-Wahhab, Olivier Joubert, Yasser A. Khadrawy, Ramia Safar, Aziza A. El-Nekeety, Carole Ronzani, Hussein G. Sawie, Nabila S. Hassan, Luc Ferrari, Bertrand H. Rihn
DOI: 10.7324/JAPS.2017.70726Pages: 176-185
A Novel Approach of Potent Antioxidant and Antimicrobial Agents Containing Coumarin Moiety Accompanied with Cytotoxicity Studies on the Newly Synthesized Derivatives
Huda R. M. Rashdan, Sami M. Nasr, Heba A. El-Refai, Mohamed S. Abdel-Aziz
DOI: 10.7324/JAPS.2017.70727Pages: 186-196
LC-ESI-MS profile, antioxidant activity and cytotoxic screening of Oligomeris linifolia (Vahl) Macbr. (Resedaceae)
Ali M. El-Hagrassy, Ahmed Elkhateeb, Sameh R. Hussein, El-Sayed S. Abdel-Hameed, Mona M. Marzouk
DOI: 10.7324/JAPS.2017.70807Pages: 043-047
Determining the Apoptotic-Inducing Property of Isothiocyanates Extracted from Three Cultivars of Raphanus sativus Linn. Using the Comet Assay
Maria Carmen S. Tan, Ma. Luisa D. Enriquez, Rechel G. Arcilla, Marissa G. Noel
DOI: 10.7324/JAPS.2017.70906Pages: 044-051
Design, synthesis, molecular docking and cytotoxicity evaluation of some novel 5-arylidene-3-(substituted phenyl)-2-(p-tolylamino)-4-imidazolones
Ahmed I. Khodair, Mostafa M. Elbadawi, Mohammed T. Elsaady, Khaled R. A. Abdellatif
DOI: 10.7324/JAPS.2017.70908Pages: 058-068
In silico Determination of Efficiency of Plant Secondary Metabolites to Eradicate Trachoma- A Blinding Keratoconjuctivitis Disease
R. Sathishkumar, R. Tharani
DOI: 10.7324/JAPS.2017.70916Pages: 116-121
Effectiveness and Safety of Colistin in Multi Drug Resistant Urinary Tract Infections
Jismy Karakkattu, Anisha Mohan, Emmanuel James, Anil Kumar
DOI: 10.7324/JAPS.2017.70920Pages: 148-152
Paracetamol Overdose Induces Physiological and Pathological Aberrations in Rat Brain
Amina E. Essawy, Afrah F. Alkhuriji, Ahmed A. Soffar
DOI: 10.7324/JAPS.2017.70925Pages: 185-190
Prenatal developmental toxicity evaluation of IDM01, a botanical composition of 4\ €‘hydroxyisoleucine and trigonelline based standardized fenugreek seed extract, during organogenesis period of pregnancy in rats
Pallavi Deshpande, Vishwaraman Mohan, K R Raghunatha Reddy, V R L N Manjunath, Prasad Thakurdesai
DOI: 10.7324/JAPS.2017.71009Pages: 062-069
Anthelmintic potential and in vivo acute toxicity study of Piptadenia gonoachanta leaf aqueous extract
Mariana Costa Fausto, Idelvânia dos Anjos Nonato, Guilherme Costa Fausto, Rogério Pinto, Fabrício Luciani Valente, Lorendane Millena de Carvalho, Artur Kanadani Campos, Marcelo Barcellos da Rosa, Jackson Vitor de Araújo1 , Camilo Amaro de Carvalho
DOI: 10.7324/JAPS.2017.71016Pages: 111-117
Chemical composition and biological activities of methanol extract from Macrocybe lobayensis
Somanjana Khatua, Sandipta Ghosh, Krishnendu Acharya
DOI: 10.7324/JAPS.2017.71021Pages: 144-151
Hesperidin protects against diethylnitrosamine/carbon tetrachloride-induced renal repercussions via up-regulation of Nrf2/HO-1 signaling and attenuation of oxidative stress
Magdy S. Aly, Sanaa R. Galaly, Nadia Moustafa, Hanaa M. Mohammed, Sally M. Khadrawy, Ayman M. Mahmoud
DOI: 10.7324/JAPS.2017.71102Pages: 007-014
Evaluation Antioxidant and cytotoxic activities of novel chitooligosaccharides prepared from chitosan via enzymatic hydrolysis and ultrafiltration
Sanaa T. El-Sayed, Nagwa I. Omar, El-Sayed M. El-Sayed, Wafaa G. Shousha
DOI: 10.7324/JAPS.2017.71107Pages: 050-055
Renoprotective Effect of Centaurea choulettiana Pomel (Asteraceae) Leaves on Cisplatin-induced Oxidative Stress and Renal dysfunction in Mice
Bioud Kenza, Azzouzi Djihane, Benrebai Mouad, Mekkiou Ratiba, Benayache Samir, Benayache Fadila, Ameddah Souad
DOI: 10.7324/JAPS.2017.71122Pages: 147-154
Dose Response Study of a Novel Gold-Manganese Oxide Nano-Composite in an In Vivo Murine Model
Anupam Nath, Ramkrishna Pal, Leichombam Mohindro Singh, Himadri Saikia, Hasimur Rahaman, Sujit Kumar Ghosh, Ritwik Mazumder, Mahuya Sengupta
DOI: 10.7324/JAPS.2017.71204Pages: 028-037
Cytotoxic activity screening of ethyl acetate fungal extracts derived from the marine sponge Neopetrosia chaliniformis AR-01
Muh. Ade Artasasta, Yanwirasti, Akmal Djamaan, Dian Handayani
DOI: 10.7324/JAPS.2017.71225Pages: 174-178
Synthesis And Anticancer Screening Of Novel Spiro[Chroman-2,4′- Piperidin]-4-One Derivatives With Apoptosis-Inducing Activity
Shaimaa A. Abdelatef, Mohammed T. El-Saadi, Noha H. Amin, Ahmed H. Abdelazeem, Khaled R.A. Abdellatif
DOI: 10.7324/JAPS.2018.8102Pages: 009-016
Cytotoxic Activity Screening of Fungal Extracts Derived from the West Sumatran Marine Sponge Haliclona fascigera to Several Human Cell Lines: Hela, WiDr, T47D and Vero
Dian Handayani, Wildan Rasyid, Rustini, Elmi Nurhaidah Zainudin, Triana Hertiani
DOI: 10.7324/JAPS.2018.8109Pages: 055-058
Synthesis and Cytostatic Activity of 4-bromo-5-ethyl-2-(ethylamino)- 5-methyl-5H-1,2-oxaphosphole 2-oxide
Dobromir D. Enchev, Vanya P. Koleva, Asya P. Dragoeva, Leman B. Behchet-Ibryam, Mihail N. Mihaylov, Nikolay M. Uzunov, Laura Melendez-Alafort, Antonio Rosato , Valery Brel
DOI: 10.7324/JAPS.2018.8112Pages: 080-086
6-shogaol from ginger oleoresin loaded liposomes using DMPG-Na as a carrier enhances the in-vitro and in-vivo anticancer activity
Kiran Kemkar, Sathiyanarayanan L., Arulmozhi Sathiyanarayanan, Kakasaheb Mahadik
DOI: 10.7324/JAPS.2018.8201Pages: 001-010
Antimicrobial and Cytotoxic Activities of Endophytic Fungi Isolated from Mangrove Plant Sonneratia alba Sm
Dian Handayani, Harrizul Rivai, Rizka Mulyana, Netty Suharti, Roslaili Rasyid, Triana Hertiani
DOI: 10.7324/JAPS.2018.8207Pages: 049-053
Sildenafil, a phosphodiesterase-5-inhibitor decreased the oxidative stress induced by carbon tetrachloride in the rat kidney: A preliminary study
Anne A. Adeyanju, Olorunfemi R. Molehin, Ezekiel T. Ige, Lanre O. Adeleye, Oluwakemi V. Omoniyi
DOI: 10.7324/JAPS.2018.8217Pages: 106-111
Monitoring the cellular uptake of Silica-Coated CdSe/ZnS quantum dots by Time lapse Confocal Laser Scanning Microscopy
Heba ElSayed ElZorkany, Haidan M. El-Shorbagy, Khaled Yehia Farroh, Tareq Youssef, Salwa Sabet, Taher A. Salaheldin
DOI: 10.7324/JAPS.2018.8301Pages: 001-008
Cisplatin-Induced Nephrotoxicity in Rats: Modulatory Role of Simvastatin and Rosuvastatin against Apoptosis and Inflammation
Rasha E. Mostafa, Dalia O. Saleh, Dina F. Mansour
DOI: 10.7324/JAPS.2018.8406Pages: 043-050
Physical Signs of Illness, Liver Functions and Reproductive Parameters of Female Rats Supplemented with Melaleuca cajuputi Methanolic Extract
Dzulsuhaimi Daud, Nur Lisma Ruhila Alias, Mohd Tajudin Mohd Ali, Alene Tawang
DOI: 10.7324/JAPS.2018.8420Pages: 139-142
Atorvastatin-Induced Hepatotoxicity, Increased by Clopidogrel Stress on CYP450 Enzyme: Understanding the Mechanism through a Case
Sahithi Thotakura, Ajit Singh, Kanav Khera, Sheetal Chauhan, Tom Devasia
DOI: 10.7324/JAPS.2018.8424Pages: 168-170
Uranium-induced Cytotoxicity in HEK 293T Cells is reduced by a β-glucan type Exopolysaccharide produced by Enterobacter sp. YG4
K. K. Nagaraj, A. B. Arun, P. D. Rekha
DOI: 10.7324/JAPS.2018.8425Pages: 171-173
Cisplatin-Etoposide Induced Myocardial Infarction in a Patient with Small Cell Carcinoma
Srija Katta, Sheetal Chauhan, Ajit Singh, Prasad N. Shetty, Hashir Kareem, Tom Devasia
DOI: 10.7324/JAPS.2018.8519Pages: 139-142
Pharmacological potentials and toxicity effects of Excoecaria agallocha
Eric Wei Chiang Chan, Nozomi Oshiro, Mio Kezuka, Norimi Kimura, Karin Baba, Hung Tuck Chan
DOI: 10.7324/JAPS.2018.8523Pages: 166-173
Ethanolic extract of pomegranate (Punica granatum L) peel: acute toxicity tests on zebrafish (Danio rerio) embryos and its toxicity prediction by in silico
Indra Wibowo, Kurnia Permadi, Rika Hartati, Sophi Damayanti
DOI: 10.7324/JAPS.2018.8611Pages: 082-086
Acute and sub-chronic toxicity studies of Dichaetanthera africana (Hook. F.) Jacq. Fel. (Melastomataceae) stem bark ethanol extract
Aristide Laurel Mokale Kognou, Armelle Deutou Tchamgoue, Lauve Rachel Yamthe Tchokouaha, Dominic Ngima Nthenge-Ngumbau, Patrick Valere Tsouh Fokou, Alembert Tiabou Tchinda, Gabriel Agbor Agbor, Rebecca Madeleine Ebelle Etame1 , Raymond Simplice Mouokeu, Cecile Enguehard Gueiffier, Rajesh Singh Pawar, Albert Sone Mouelle, Rosalie Annie Ngono Ngane
DOI: 10.7324/JAPS.2018.8619Pages: 147-155
Evaluation of Antioxidant, Thrombolytic and Cytotoxic Potentials of Methanolic Extract of Aporosa wallichii Hook.f. Leaves: An Unexplored Phytomedicine
Shahana Sharmin, Md. Tanvir Kabir, Md. Nasiful Islam, Mohd. Raeed Jamiruddin, Imon Rahman, Arifur Rahman, Mahboob Hossain
DOI: 10.7324/JAPS.2018.8709Pages: 051-056
Chemical and Cytotoxic Investigation of Non-Polar Extract from Ceiba pentandra (L.) Gaertn.: A Study Supported by Computer Based Screening
Mohamed E. Abouelela, Mohamed A. A. Orabi, Reda A. Abdelhamid, Mohamed S. A. Abdelkader, Faten M. M. Darwish
DOI: 10.7324/JAPS.2018.8710Pages: 057-064
Antibacterial and cytotoxicity activities of phenylbutanoids from Zingiber cassumunar Roxb.
Thongchai Taechowisan, Savoranee Suttichokthanakorn, Waya S. Phutdhawong
DOI: 10.7324/JAPS.2018.8719Pages: 121-127
Production and characterization of exopolysaccharide from marine Bacillus sp. MSHN2016 with studying its effect on isoniazid/ rifampicin-induced hepatic and renal toxicities in rats
Manal S. Selim, Sahar S. Mohamed, Mohsen M. Asker, Abeer A.A. Salama, Heba M.I Abdallah, Noha N. Yassen
DOI: 10.7324/JAPS.2018.8801Pages: 001-011
Coumarins from Creston Apple Seeds: Isolation, Chemical Modification, and Cytotoxicity Study
Yasser Fakri Mustafa, Moath Abdulla Najem, Zena Sideek Tawffiq
DOI: 10.7324/JAPS.2018.8808Pages: 049-056
Synthesis, Characterization of Novel PLGA Encapsulated Indole Nanoparticles and Study of its cytotoxic potential against A549 lung cancer cell line
Sudip Majumder, Neha Sharma, Subhra Das, Namita Pandey, Tapasya Srivastava, Debasree Ghosha
DOI: 10.7324/JAPS.2018.8820Pages: 144-150
Biological potential of Citharexylum myrianthum Cham. leaves in vitro and phenolic profile by HPLC-ESI-MS/MS
Adrielli Tenfen, Camile Cecconi Cechinel-Zanchett, Ana Paula Dalmagro, Priscila Zimath, Ariela Maína Boeder, Gabriel M. D. Santos, Adriana Campos, Diogo Alexandre Sibert, Gustavo Micke, Luciano Vitali, Caio Maurício Mendes de Córdova, Alexandre Bella-Cruz, Rivaldo Niero, Valdir Cechinel-Filho
DOI: 10.7324/JAPS.2018.8911Pages: 074-080
In-vitro cytotoxicity and apoptosis mechanism of ethyl acetate extract from Trichoderma reesei strain TV221 associated with marine sponge: Stylissa flabelliformis
Erna Prawita Setyowati, Sylvia Utami Tunjung Pratiwi, Purwantiningsih, Indah Purwantini
DOI: 10.7324/JAPS.2018.8921Pages: 151-157
Evaluation of selected echinoderms from peninsular Malaysia for cytotoxicity against HepG2 cells, antioxidant and antibacterial activities, and their metabolites profiling
Yosie Andriani, Nurul Hazirah Mat Lazim, Asnuzilawati Asari, Faridah Mohamad, Tengku Sifzizul Tengku Muhammad, Noraznawati Ismail, Mariam Taib, Hermansyah Amir, Aziz Ahmad, Habsah Mohamad
DOI: 10.7324/JAPS.2018.81005Pages: 032-038
Toxicity Studies on Leaf Extracts of Alternanthera brasiliana (L.) Kuntze and Alternanthera bettzickiana (Regel) Voss
Kasthuri O R, Ramesh B
DOI: 10.7324/JAPS.2018.81011Pages: 082-089
Garcinia binucao crude ethanolic leaf extract prevents alcohol-induced neurotoxic effects on learning, short-term memory, and motor functions in Drosophila melanogaster
Ourlad Alzeus G. Tantengco, Joanne Jennifer E. Tan, Nicholas Robert C. Tan, Maria Concepcion C. Sison, Paul Mark B. Medina
DOI: 10.7324/JAPS.2018.81014Pages: 106-112
Cytotoxic effects and anti-proliferative cancer activity of coelomic fluid from Lumbricus rubellus promotes apoptosis and reduces G2/M phase progression in HT-29 cells
Sofy Permana, Pearlindah, Zurniatus Sholihah, Agustin Iskandar, Hani Susanti, Agustina Tri Endharti
DOI: 10.7324/JAPS.2018.81104Pages: 028-034
Pharmacological evaluation of ethnomedicinal Glycosmis pentaphylla Lour. as antidiabetic, antioxidant and cytotoxic agent
Mohammad Oliur Rahman, Mohammad Badiur Rahman, Shah Alam Siddiqui, Mohammad Abul Hassan, Mohammad Abdur Rashid
DOI: 10.7324/JAPS.2018.81112Pages: 080-086
The effects of individual and combination of asiatic acid and madecassoside derived from Centella asiatica (Linn.) on the viability percentage and morphological changes of mouse macrophage cell lines (J774A.1)
Nurul Hikmah Harun, Wan Amir Nizam Wan Ahmad, Rapeah Suppıan
DOI: 10.7324/JAPS.2018.81116Pages: 109-115
Evaluation of Indonesian selected macroalgae for their antitumor and cytoprotective activity
Eka Sunarwidhi Prasedya, Mutiadevi Ariyana, Candra Dwipayana Hamdin, Aluh Nikmatullah, Susumu Yoshie, Masao Miyake, Daisuke Kobayashi, Akihiro Hazama, Haji Sunarpi
DOI: 10.7324/JAPS.2018.81118Pages: 123-130
Screening of cytotoxic activities toward WiDr and Vero cell lines of ethyl acetate extracts of fungi-derived from the marine sponge Acanthostrongylophora ingens
Ibtisamatul Aminah, Andani Eka Putra, Dayar Arbain, Dian Handayani
DOI: 10.7324/JAPS.2019.90101Pages: 001-005
Hepatotoxicity associated with statins: Role of drug interactions
Estrella Martínez-Gómez, Laura Sanz Villanueva, Cecilio Parra-Martínez, Inmaculada Medina-Cáliz, M. Isabel Lucena
DOI: 10.7324/JAPS.2019.90120Pages: 147-148
Antitumor activities of new iso(thio)cyanates and their nitrogen and sulphur heterocyclic phosphorus derivatives
Mansoura A. Abd-El-Maksoud, Aida I. El-Makawy, Sekena H. Abdel-Aziem, Soher S. Maigali, Marwa El-Hussieny, Shaimaa T. Mansour, Fouad M. Soliman
DOI: 10.7324/JAPS.2019.90201Pages: 001-011
A natural approach to control induced fumonisin B1-histopathological nephrotoxic and hepatotoxic changes in rats
Ashraf A Khalil, Ashgan Abou Gabal, Amira A Abdellatef, Noha M Zahran, Sahar F Deraz
DOI: 10.7324/JAPS.2019.S103Pages: 017-029
Cressa cretica L. growing in Egypt: Phytochemical study and potential antioxidant and hepato-protective activities
Taha S. El-Alfy, Nagwa M. Ammar, Sahar Y Al-Okbi, Maha M Salama, Hanan F. Aly, Asmaa A Amer
DOI: 10.7324/JAPS.2019.S106Pages: 046-057
ZnO nanoparticles: Crosslink between cytotoxicity on liver cell lines and In Vivo biosafety on different mice organs
Nahla Nabil Kamel, Maha Zaki Rizk, Walaa Gamal Hozayen, Abdel-Hamid Zaki Abdel-Hamid
DOI: 10.7324/JAPS.2019.S107Pages: 058-066
Synthesis, anticancer activity, and docking study of N-acetyl pyrazolines from veratraldehyde
Tutik Dwi Wahyuningsih, Artania Adnin Tri Suma, Endang Astuti
DOI: 10.7324/JAPS.2019.90303Pages: 014-020
A pilot study on effectiveness of oral mucositis pain control in hematopoietic stem cell transplant patients
Shu Ping Wong, Farida Islahudin
DOI: 10.7324/JAPS.2019.90305Pages: 027-032
N-Butylpyridoquinoxaline 1, 4-dioxide alleviates experimentally induced leukemia with up-regulating sphingosine-1-phosphate receptors
Mai M. Kabeel, Ahmed M. Ghoneim
DOI: 10.7324/JAPS.2019.90402Pages: 008-015
Camellia sinensis and epicatechin abate doxorubicin-induced hepatotoxicity in male Wistar rats via their modulatory effects on oxidative stress, inflammation, and apoptosis
Osama M. Ahmed, Manal M. Abdul-Hamid, Ahlam M. El-Bakry, Hanaa M. Mohamed, Fatma El-Zahraa S. Abdel Rahman
DOI: 10.7324/JAPS.2019.90405Pages: 030-044
Antiproliferative activity of longan (Dimocarpus longan Lour.) leaf extracts
Ratna Puspita, Maria Bintang, Bambang Pontjo Priosoeryanto
DOI: 10.7324/JAPS.2019.90513Pages: 102-106
Teratogenic effects of aqueous extract of Ficus glomerata leaf during embryonic development in zebrafish (Danio rerio)
Abusufyan Shaikh, Kalidas Kohale, Mohammed Ibrahim, Mohib Khan
DOI: 10.7324/JAPS.2019.90514Pages: 107-111
Cytotoxicity evaluation and the mode of cell death of K562 cells induced by organotin (IV) (2-methoxyethyl) methyldithiocarbamate compounds
Nurul Farahana Kamaludin, Nazifa Ismail, Normah Awang, Rapidah Mohamad, Norraphat Uttraphan Pim
DOI: 10.7324/JAPS.2019.90602Pages: 010-015
Cytotoxic and antimicrobial activities of ethyl acetate extract of mangrove plant Scyphiphora hydrophyllacea C. F. Gaertn— Associated fungi
Dian Handayani, Neny sandrawati, Rustini Ruslan, Oga Nestianda, Anzharni Fajrina, Trina Ekawati Tallei
DOI: 10.7324/JAPS.2019.90610Pages: 075-079
C-glycosyl flavonoids-rich extract of Dipcadi erythraeum Webb & Berthel. bulbs: Phytochemical and anticancer evaluations
Mona M. Marzouk, Ahmed Elkhateeb, Rasha R. Abdel Latif, El-Sayed S. Abdel-Hameed, Salwa A. Kawashty, Sameh R. Hussein
DOI: 10.7324/JAPS.2019.90613Pages: 094-098
Anti-inflammatory properties of bergenin in mice
Guilherme A. L. Oliveira, Andreza K. S. Araujo, Gabriella Pacheco, Ana P. Oliveira, Jelson L. Carvalho, Letícia S. Chaves, Gabrielle C. Sousa, André L. F. Lopes, Priscila C. Silva, Ana Carolina M. Leódido, Kerolayne M. Nogueira, Luan K. M. Souza, Thiago L. Araújo, Lucas A. D. Nicolau, Jand Venes R. Medeiros
DOI: 10.7324/JAPS.2019.90709Pages: 069-077
Short chain linear and cyclic cationic peptide designed from cecropin B: Synthesis and anticancer activity
Ravi Dutt Sharma, Jainendra Jain, Ratan Lal Khosa
DOI: 10.7324/JAPS.2019.90801Pages: 001-010
Synthesis and anticancer potential of aminomethyl derivatives of methyl-substituted asymmetrical curcumin mono-carbonyl
Arini Kurnia, Fadlina Chany Saputri, Hayun Hayun
DOI: 10.7324/JAPS.2019.90803Pages: 018-024
In vitro cytotoxic activity assay of bacteria extract derived marine sponge Haliclona fascigera toward Hela, WiDr, T47D, and Vero cell line
Neny Sandrawati, Regina Pariatno, Netty Suharti, Dian Handayani
DOI: 10.7324/JAPS.2019.90809Pages: 066-070
Antipromastigote and cytotoxic activities of some chemical constituents of Hypericum lanceolatum Lam. (Guttifereae)
Theodora K. Kowa, Lauve R. Y. Tchokouaha, Jean Noel Nyemb, Hippolyte K. Wabo, Alembert T. Tchinda, Regina Appiah-Opong, Gabriel A. Agbor, Pierre Tane, Michel Frederich
DOI: 10.7324/JAPS.2020.101004Pages: 026-032
Antiproliferative and apoptosis effect of hyptolide from Hyptis pectinata (L.) Poit on human breast cancer cells
Meiny Suzery, Bambang Cahyono, Nur Dina Amalina
DOI: 10.7324/JAPS.2020.102001Pages: 001-006
Synthesis of new boron containing compound (CCB-2) based on curcumin structure and its cytotoxic effect against cancer cells
Edy Meiyanto, Ratna Asmah Susidarti, Riris Istighfari Jenie, Rohmad Yudi Utomo, Dhania Novitasari, Febri Wulandari, Mitsunori Kirihata
DOI: 10.7324/JAPS.2020.102010Pages: 060-066
Isolation, characterization, and cytotoxic studies of secondary metabolites from the leaves of Bauhinia foveolata Dalzell: An endemic tree from the Western Ghats, India
Prasanna V. Habbu, Narayan Miskin1, Venkatrao H. Kulkarni, Pradeep Bhat, Arun Joshi, Anant Bhandarkar, Satish Kulkarni, Sheshagiri R. Dixit, Jaishree Vaijanathappa
DOI: 10.7324/JAPS.2020.103018Pages: 135-148
Antiproliferation activity of God’s crown fruit (Phaleria macrocarpa) extract and fractions against MCM-B2 breast cancer cells
Hasim Hasim, Silvi Octavia Kurniawati, Bambang Pontjo Priosoeryanto, Didah Nur Faridah, Ratna Puspita
DOI: 10.7324/JAPS.2020.103006Pages: 052-058
Antimicrobial and cytotoxic activities of marine sponge-derived fungal extracts isolated from Dactylospongia sp.
Neny Sandrawati, Shuci Permata Hati, Fujia Yunita, Andani Eka Putra, Friardi Ismed, Trina Ekawati Tallei, Triana Hertiani, Dian Handayani
DOI: 10.7324/JAPS.2020.104005Pages: 028-033
Prednisolone encapsulated PLGA nanoparticles: Characterization, cytotoxicity, and anti-inflammatory activity on C6 glial cells
Sriprasad Acharya, Bharath Raja Guru
DOI: 10.7324/JAPS.2020.104003Pages: 014-021
Acute and subacute toxicity evaluation of hydroalcoholic extract of Caryota urens leaves in Wistar rats
Sujitha Balaji, Kripa Kavasseri Ganesan
DOI: 10.7324/JAPS.2020.104015Pages: 121-128
In vitro cytotoxicity and druglikeness of pyrazolines and pyridines bearing benzofuran moiety
Asma S. Al Wasidi, Ashraf S. Hassan, Ahmed M. Naglah
DOI: 10.7324/JAPS.2020.104018Pages: 142-148
LC-MS method development for the quantitation of potential genotoxic impurity 2-Methyl-6-nitro aniline in Telmisartan API
Duvvuri Suryakala, Sivakumar Susarla, Bandlamudi Mallikarjuna Rao
DOI: 10.7324/JAPS.2020.10512Pages: 092-096
Cytotoxicity activity of geldanamycin derivatives against various cancer cell lines
Thongchai Taechowisan, Tipparat Samsawat, Winyou Puckdee, Waya S. Phutdhawong
DOI: 10.7324/JAPS.2020.10603Pages: 012-021
Isolation and identification of secondary metabolite acetone extract Aaptos sp. and its antioxidant properties and acute toxicity
Adryan Fristiohady, Baru Sadarun, Wahyuni Wahyuni, Muhammad Hajrul Malaka, Fandi Ahmad, Fadhliyah Malik, La Ode Muhammad Julian Purnama, Idin Sahidin
DOI: 10.7324/JAPS.2020.10611Pages: 081-089
Optimization of pancreatic islet isolation from rat and evaluation of islet protective potential of a saponin isolated from fruits of Momordica dioica
Suman Samaddar, Deepak K. Jha, Raju Koneri
DOI: 10.7324/JAPS.2020.10712Pages: 089-099
A review on phytochemical constituents, role on metabolic diseases, and toxicological assessments of underutilized part of Garcinia mangostana L. fruit
Abdul Rohman, Fitriana Hayyu Arifah, Irnawati, Gemini Alam, Muchtaridi, Muhammad Rafi
DOI: 10.7324/JAPS.2020.10716Pages: 127-146
A Schiff base of 2-((E)-(2-amino-5-methylphenylimino)methyl)- 5-(difluoromethoxy)phenol and its applications on fluorescent chemosensor for selection of Mg2+ ion, molecular docking, and anticancer activity
Iyappan Mathivanan, Dhineshkumar Ezhumalai, Anbuselvan Chinnadurai
DOI: 10.7324/JAPS.2020.10809Pages: 075-085
Characterization, in vitro cytotoxic and antibacterial exploitation of green synthesized freshwater cyanobacterial silver nanoparticles
Guna Swetha Kuraganti, Sujatha Edla, Thrimothy Dasari, Mamatha Reddy
DOI: 10.7324/JAPS.2020.10911Pages: 088-098
Purification, characterization, and antiproliferative activity of L-methioninase from a new isolate of Bacillus haynesii JUB2
Brinda Bojamma Kotramada Bopaiah, Diana Aiyandra Nanda Kumar, Kohini Balan, Lucky Dehingia, Manoj Kumar Ramanayakanahalli Venkatesh Reddy, Ashrini Bhaktavalsala Suresh, Varalakshmi Kilingar Nadumane
DOI: 10.7324/JAPS.2020.10106Pages: 054-061
Genistein enhances cytotoxic and antimigratory activities of doxorubicin on 4T1 breast cancer cells through cell cycle arrest and ROS generation
Muthi Ikawati, Riris Istighfari Jenie, Rohmad Yudi Utomo, Nur Dina Amalina, Gagas Pradani Nur Ilmawati, Masashi Kawaichi, Edy Meiyanto
DOI: 10.7324/JAPS.2020.1010011Pages: 095-104
Synthesis and cytotoxic evaluation of novel chromenes and chromene(2,3-d)pyrimidines
Mahmoud N. M. Yousif, Abdel-Rahman B. A. El-Gazzar, Ahmed A. Fayed, May A. El-Manawaty, Nabil M. Yousif
DOI: 10.7324/JAPS.2020.101205Pages: 035-043
A new triterpene saponin from Fagonia schimperi
Howayda Ismail, Mohamed E. Mostafa, Amr El-Demerdash, Dalia M. Hanna, Mamdouh Abdel-Mogib
DOI: 10.7324/JAPS.2020.101209Pages: 068-074
Marine Sponge-Derived Fungi: Fermentation and Cytotoxic Activity
Putu Oka Samirana, Yosi Bayu Murti, Riris Istighfari Jenie, Erna Prawita Setyowati
DOI: 10.7324/JAPS.2021.110103Pages: 021-039
Novel hydroxycinnamamide from morpholine and pyrrolidine: Synthesis, characterization, docking study, and anticancer activity against P388 leukemia murine cells
Firdaus, Nunuk Hariani Soekamto, Syadza Firdausiah, Herlina Rasyid, Nur Asmi, Muzdalifah Waelulu
DOI: 10.7324/JAPS.2021.110104Pages: 040-048
Reproductive safety assessment of Thymus vulgaris L. extract and quantification of thymol sulfate in pregnant rats and fetuses using a validated LC/MS method of analysis
Zaineh Q. Tafesh, Kenza A. Mansoor, Nidal A. Qinna, Feras D. El-Hajji, Tawfiq A. Arafat, Luay F. Abu-Qatouseh, Bayan Y. Ghanim, Iman A. Basheti, Eyad M. Mallah
DOI: 10.7324/JAPS.2021.110117Pages: 144-151
Evaluation of the renoprotective effect of syringic acid against nephrotoxicity induced by cisplatin in rats
Hardevinder Pal Singh, Thakur Gurjeet Singh, Randhir Singh
DOI: 10.7324/JAPS.2021.11s109Pages: 080-085
Nature of hematopoietic system alteration and organ damage induced by fungal filtrate of Pestalotiopsis microspora in vivo
Taofeeq Garuba, Adebola Azeez Lateef, Soliu Abiola Atunwa, Abibat Yetunde Lateef, Olajumoke Oluwabunmi Kolawole, Saheed Sabiu
DOI: 10.7324/JAPS.2021.110309Pages: 084-091
A study to evaluate the hepatoprotective activity of prebiotics, probiotics, and synbiotic in CCl4 induced hepatotoxicity in rats
Aswad B. Devi, Anand B. Rahigude, Pradeep B. Parab, Anupama S. Engineer, Prashant K. Dhakephalkar, Kishori G. Apte
DOI: 10.7324/JAPS.2021.110317-1Pages: 141-153
Diosmetin and tamarixetin (methylated flavonoids): A review on their chemistry, sources, pharmacology, and anticancer properties
Eric Wei Chiang Chan, Ying Ki Ng, Chia Yee Tan, Larsen Alessandro, Siu Kuin Wong, Hung Tuck Chan
DOI: 10.7324/JAPS.2021.110302Pages: 022-028
Non-clinical toxicological evaluation of the ethanolic extract from Zornia brasiliensis Vogel (Fabaceae)
Tatianne Batista, Renata Abrantes, Aline Xavier, João Carlos Pita, Monalisa Brito, Adriano Alves, Anne Dayse, Yuri Nascimento, Sócrates Santos, Josean Tavares, Marcelo Silva, Marianna Sobral
DOI: 10.7324/JAPS.2021.110409Pages: 068-075
Goniothalamus lanceolatus extract inhibits the growth of human ovarian cancer cells through migration suppression and apoptosis induction
Nasibah Razali, Norodiyah Othman, Nur Hilwani Ismail, Nur Vicky Bihud, Nor Hadiani Ismail, Farida Zuraina Mohd Yusof
DOI: 10.7324/JAPS.2021.110410Pages: 076-087
Exploring the potentials of selected bioactive compounds isolated from Piper guineense Schumach. & Thonn. leaf toward identification of novel pfDHFR and pfDHODH inhibitors as antimalaria agents
Oluwafemi Adeleke Ojo
DOI: 10.7324/JAPS.2021.110418Pages: 153-158
A minireview on phytochemical and medicinal properties of Clinacanthus nutans
Peik Lin Teoh
DOI: 10.7324/JAPS.2021.110602Pages: 015-021
Phytoconstituents with cytotoxic activity from Ulmus pumila L.
Farouk R. Melek, Soheir M. El Zalabani, Neveen S. Ghaly, Omar M. Sabry, Walid Fayad, Ann G. Boulis
DOI: 10.7324/JAPS.2021.110517Pages: 127-134
Cytotoxicity screening of cotreatment with temozolomide and azithromycin on human glioblastoma cells U87
Siti Nazihahasma Hassan, Abdul Aziz Mohamed Yusoff, Norhanani Mohd Redzwan, Zamzuri Idris, Farizan Ahmad
DOI: 10.7324/JAPS.2021.110417Pages: 145-152
In vitro antibacterial, antioxidant, and cytotoxicity evaluations of Musa paradisiaca cv. Sekaki florets from Sarawak, Malaysia
Muhammad Mirza Ariffin, Heng Yen Khong, Nyotia Nyokat, Gee Moi Liew, Ahmad Sazali Hamzah, Korawinwich Boonpisuttinant
DOI: 10.7324/JAPS.2021.110513Pages: 091-099
Evaluation of fucoidan from Sargassum duplicatum on performance immune responses, serum biochemical, and hematological testing in rats
Ellya Sinurat, Endar Marraskuranto, Subaryono Subaryono
DOI: 10.7324/JAPS.2021.110618Pages: 146-153
Nephroprotectivity of Coccinia indica leaves against gentamycin-induced nephrotoxicity using in vitro and in vivo models
Neelima Satrasala, Dwarakanadha Reddy Peram, Chandra Sekhar Kothapalli Bannoth
DOI: 10.7324/JAPS.2021.110616Pages: 132-139
Evaluation of antioxidant and cytotoxic effect against cancer cells line of Angiopteris ferox Copel tuber and its compounds by LC-MS analysis
Syamsu Nur, Andi Nur Aisyah, Endang Lukitaningsih, Rumiyati, Rini Indriani Juhardi, Rezkiawati Andirah, Andi Sitti Hajar
DOI: 10.7324/JAPS.2021.110808Pages: 054-061
Antioxidant and cytotoxicity activity of Cordyceps militaris extracts against human colorectal cancer cell line
Mohd Azrie Awang, Nik Nurul Najihah Nik Mat Daud, Nurul Izzati Mohd Ismail, Poh Guat Cheng, Mohd Fakhrulddin Ismail, Shiamala Devi Ramaiya
DOI: 10.7324/JAPS.2021.110711Pages: 105-109
Synthesis, cytotoxicity, and promising anticancer potential of novel β-amino- and β-iminophosphonates
Vanya Koleva, Irina Yotova, Asya Dragoeva, Dobromir Enchev
DOI: 10.7324/JAPS.2021.110708Pages: 080-088
Isolation, peroxisome proliferator-activated receptor-gamma transcription, glucose uptake, and molecular docking of tetramethoxyflavonoids from the leaves of Rourea mimosoides (Vahl) Planch.
Che Puteh Osman, Norhafizoh Abdul Somat, Zuriati Zahari, Syahrul Imran, Mohd Ilham Adenan
DOI: 10.7324/JAPS.2021.110802Pages: 010-016
Cytotoxicity and antibacterial activities of crude extract of Streptomyces sp. W08, an endophyte of Amomum krervanh Pierre
Thongchai Taechowisan, Tipparat Samsawat, Winyou Puckdee, Waya S. Phutdhawong
DOI: 10.7324/JAPS.2021.110818Pages: 134-138
Evaluating the effect of dopamine-geldanamycin hybrids on anticancer activity
Thongchai Taechowisan, Tipparat Samsawat, Chanjira Jaramornburapong, Weerachai Phutdhawong, Waya S. Phutdhawong
DOI: 10.7324/JAPS.2021.110713Pages: 117-126
Cytotoxic activity of seaweeds from North Sulawesi marine waters against cervical cancer
Grace Sanger, Lexy Karel Rarung, Djuhria Wonggo, Verly Dotulong, Lena Jeane Damongilala, Trina Ekawati Tallei
DOI: 10.7324/JAPS.2021.110908Pages: 066-073
Immunopotentiation of galangal (Alpinia galanga L.) when combined with T-cells against metastatic triple-negative breast cancer, MDA-MB 231
Iffan Alif, Rohmad Yudi Utomo, Faradiba Nur Ahlina, Nadzifa Nugraheni, Dedy Hermansyah, Agung Putra, Edy Meiyanto
DOI: 10.7324/JAPS.2021.1101107Pages: 053–061
Synthesis, preliminary anticonvulsant and toxicity screening of substituted {1-[4-Methyl-2-substitutedphenyl-2,5-dihydro-1,5- benzothiazepin-3-yl]-ethylidene}-hydrazine
Vikash Kumar Chaudhri, Devender Pathak, Zeashan Hussain
DOI: 10.7324/JAPS.2021.1101003Pages: 016-023
Yellow pigment from a novel bacteria, Micrococcus terreus, activates caspases and leads to apoptosis of cervical and liver cancer cell lines
Megha Shukla, Varalakshmi Kilingar Nadumane
DOI: 10.7324/JAPS.2021.110811Pages: 077-084
Evaluating the effect of amine-geldanamycin hybrids on anticancer activity
Tipparat Samsawat, Chanjira Jaramornburapong, Weerachai Phutdhawong, Waya S. Phutdhawong, Thongchai Taechowisan
DOI: 10.7324/JAPS.2021.110814Pages: 098-107
A new curcumin analog, CCA-1.1, induces cell death and cell cycle arrest in WiDr colon cancer cells via ROS generation
Febri Wulandari, Muthi Ikawati, Mitsunori Kirihata, Jun-Ya Kato, Edy Meiyanto
DOI: 10.7324/JAPS.2021.1101014Pages: 099-105
Anti-inflammatory effect and acute oral toxicity of 4-methoxycinnamyl p-coumarate isolated from Etlingera pavieana rhizomes in animal models
Natthakarn Chiranthanut, Nirush Lertprasertsuke, Ekaruth Srisook, Klaokwan Srisook
DOI: 10.7324/JAPS.2021.1101004Pages: 024-028
Antibacterial and cytotoxic activities of supernatant and mycelium extracts from fermentation of fungal symbiont Trichoderma reesei TV221
Putu Oka Samirana, Yosi Bayu Murti, Riris Istighfari Jenie, Erna Prawita Setyowati
DOI: 10.7324/JAPS.2021.1101207Pages: 090–099
Potential anticancer activities of chloroform subfraction from Peronema leaf on colon cancer HT-29 cells in vitro
Arsyik Ibrahim, Siswandono Siswandono, Bambang Prajogo Eko Wardojo
DOI: 10.7324/JAPS.2021.1101206Pages: 082–089
Utilization of physical and chemical microbial load reduction agents for SARS-CoV-2: Toxicity and development of drug resistance implications
Sani Yahaya Najib, Yusuf Oloruntoyin Ayipo, Abubakar Shaaban, Mohd Nizam Mordi, Abdullahi Rabiu Abubakar, Adekunle Babajide Rowaiye, Sayeeda Rahman, Rahnuma Ahmad, Bushra Ayat Meghla, Nihad Adnan, Mainul Haque
DOI: 10.7324/JAPS.2021.120101Pages: 001-028
Potential protein antiglycation, antiproliferation, and in silico study on the antidiabetic enzymes of bioactive metabolites from Adonis microcarpa DC and their ADMET properties
Howaida Ibrahim Abd-Alla, Amal Zaki Hassan, Maha Mohamed Soltan, Ahmed Baker Abdelwahab, Atef Gobran Hanna
DOI: 10.7324/JAPS.2021.120110Pages: 106-119
In vitro cytotoxicity of ethanolic extract of the leaf of Calotropis gigantea from Ie Jue Geothermal Area, Aceh-Indonesia, and its mouthwash formulation against dental pulp cells
Diana Setya Ningsih, Rinaldi Idroes, Boy M. Bachtiar, Khairan Khairan, Trina Ekawati Tallei, Muslem Muslem
DOI: 10.7324/JAPS.2021.120213Pages: 133-143
New hybrid scaffolds based on ASA/genistein: Synthesis, cytotoxic effect, molecular docking, drug-likeness, and in silico ADME/Tox modeling
Lizeth Gómez-R, Gustavo Moreno-Q, Angie Herrera-R, Wilson Castrillón-L, Andrés F. Yepes, Wilson Cardona-G
DOI: 10.7324/JAPS.2021.120203Pages: 015–030
Synergistic effect of Paclitaxel and Curcumin in nano-formulations on U87 and A549 cancer cell lines
Joyceline Praveena, Sushruta S. Hakkimane, Bharath Raja Guru
DOI: 10.7324/JAPS.2021.120204Pages: 031-047
Quillaja saponaria bark saponin attenuates methotrexate induced hepatic oxidative stress, inflammation and associated liver injury in rats
Mustafa Ahmed Abdel-Reheim, Ahmed Amine Ashour, Mohamed Abdelrazik Khattab, Ahmed Gaafar A. Gaafar
DOI: 10.7324/JAPS.2022.120510Pages: 129-141
Natural extracts derived from marine sponge-associated bacteria with diverse nonribosomal peptide synthetase genes have anticancer activities
Jepri Agung Priyanto, Widya Esti Purwaningtyas, Dewi Ferantika, Dudi Tohir, Rika Indri Astuti, Aris Tri Wahyudi
DOI: 10.7324/JAPS.2022.120406Pages: 054-063
Acute toxicity evaluation and immunomodulatory potential of hydrodynamic cavitation extract of citrus peels
Dyaningtyas Dewi Pamungkas Putri, Gergorius Gena Maran, Yuni Kusumastuti, Ratna Asmah Susidarti, Edy Meiyanto, Muthi Ikawati
DOI: 10.7324/JAPS.2022.120415Pages: 136-145
Synthesis and in vitro cytotoxic activity of novel indazole analogues of curcumin against MCF-7, HeLa, WiDr, and vero cell lines
Hariyanti Hariyanti, Arry Yanuar, Kusmardi Kusmardi, Hayun Hayun
DOI: 10.7324/JAPS.2022.120420Pages: 179-184
Promising chitosan-alginate combination for rifampicin dry powder inhaler to target active and latent tuberculosis
Kurnia Sari Setio Putri, Laily Syahri Ramadhani, Theodora Rachel, Gatot Suhariyono, Silvia Surini
DOI: 10.7324/JAPS.2022.120507Pages: 098-103
Antimicrobial activity of the PEGylated antibiotic enrofloxacin and its functional and structural effect on the liver in rats
Oksana Zelenina, Vasyl Vlizlo, Mariya Kozak, Dmytro Ostapiv, Volodymyr Samaryk, Iryna Dron, Taras Stetsko, Maryna Skrypka, Viktor Tomchuk, Oleksii Danchuk, Anna Levchenko
DOI: 10.7324/JAPS.2022.120607Pages: 068-075
The quandary of incorrect practice toward unused and expired pharmaceutical products in households
Ali Al-Samydai, Maha N. Abu Hajleh, Mahmood Al-Samydai, Lidia Kamal Al-Halaseh Shahd Habash, Dania Alkhayyat, Sameera Abu Saef, Leen Haitham, Hadeel Sayel Bahloul, Majd Waleed Askender
DOI: 10.7324/JAPS.2022.120620Pages: 210-214
Simpor leaf extract (Dillenia suffruticosa Martelli) induced apoptosis of the MCF-7 and HepG2 cell lines
Sri Rahayu, Jungshan Chang, Atin Supiyani, Arief Prasetiyo
DOI: 10.7324/JAPS.2023.121327Pages: 107-113
Cholesterol-conjugated polyethylenimine 25K for safe gene delivery into human carcinoma cells
Wanlop Weecharangsan, Boon-ek Yingyongnarongkul, Praneet Opanasopit
DOI: 10.7324/JAPS.2022.120902Pages: 011-016
A triterpenoid friedelan-3ß-ol isolated from Euphorbia lactea exhibited cytotoxic activity against HN22 cells by inducing an S-phase cell cycle arrest
Pawaris Wongprayoon, Sucharat Leelasart, Jintana Jantham, Yupa Pootaeng-on, Sittisak Oekchuae, Panupun Limpachayaporn, Kanok-on Rayanil, Purin Charoensuksai
DOI: 10.7324/JAPS.2022.121004Pages: 031-048
Assessment of the genotoxicity and cytotoxicity of etazolate in cultured human lymphocytes
Yasmine Z. Al Halabi, Omar F. Khabour, Karem H. Alzoubi
DOI: 10.7324/JAPS.2022.121013Pages: 125-130
Colorectal cytotoxic activities of phenolic constituents isolated from Euphorbia pseudocactus cultivated in Egypt
Mona Ismail, Marwa Hassan Ahmed, Mohamed Zaki, Abeer Moawad, Rabab Mohammed
DOI: 10.7324/JAPS.2022.121111Pages: 097-102
Discovery of novel trihybrids based on salicylic acid/isoleucine/N-acylhydrazone: A promising therapeutic opportunity in colorectal cancer
David Preciado, Gustavo Moreno, Wilson Cardona, Andres Felipe Yepes
DOI: 10.7324/JAPS.2022.121102Pages: 010-020
Trace-level analysis of genotoxic sulfonate ester impurities in teneligliptin by GC-MS
Murugan Maniavannan, Palaniappan Ilayaraja, Paramasivam Parthiban
DOI: 10.7324/JAPS.2022.121106Pages: 052-060
Proapoptotic activity of essential oils from Syzygium aromaticum, Melaleuca cajuputi, and Cymbopogon nardus on HeLa human cervical cancer cells
Happy Kurnia Permatasari, Anita Dominique Subali, Muhammad Yusuf, Holipah Holipah
DOI: 10.7324/JAPS.2022.121209Pages: 084-094
The cytotoxicity studies of phytosterol discovered from Rhizophora apiculata against three human cancer cell lines
Rahmat Kurniawan, Syaikhul Azis, Sena Maulana, Arif Ashari, Budhi A. Prasetyo, Tati Suhartati, Sukrasno Sukrasno
DOI: 10.7324/JAPS.2023.130115Pages: 156-162
Long-term oral administration of Paederia foetida decreases cytochrome P450 mRNA expression: The predictive approaches in a rat model
Phisit Pouyfung, Saruda Kuraeiad, Supabhorn Yimthiang, Tanaporn Khamphaya
DOI: 10.7324/JAPS.2023.130203Pages: 021-028
Phytochemical screening and antioxidant and cytotoxic activities of ethyl acetate subfractions of soft coral Nepthea sp. growing in Southeast Sulawesi
Idin Sahidin, Baru Sadrun, Nur Syifa Rahmatika, Agung Wibawa M. Yodha, Adryan Fristiohady, Andini Sundowo, Sofa Fajriah
DOI: 10.7324/JAPS.2023.130211Pages: 099-105
The short-term toxicity of carbon nanotubes’ aqueous dispersion administered intravenously to rats
Igor E. Kuznetsov, Yuriy I. Gubin, Natalya D. Bunyatyan, Oleg N. Kalugin, Sergiy M. Kovalenko
DOI: 10.7324/JAPS.2023.130219Pages: 175-191
Cytotoxic and antioxidant activities of flavonoids and diterpenoids from Macaranga involucrata (Roxb.) Baill
Alifia Muharram, Diah Ayu Rachmawati, Shola Mardhiyyah, Tjitjik Srie Tjahjandarie, Ratih Dewi Saputri, Norizan Ahmat, Mulyadi Tanjung
DOI: 10.7324/JAPS.2023.101645Pages: 087-092
Functionalized carbon nanotubes—A boon in treating brain diseases
Rajkumar Ghosh, Jagabandhu Bag, Aparna Datta, Arup Pramanick, Isa Hassan Abubakar
DOI: 10.7324/JAPS.2023.107158Pages: 032-039
Diosmin attenuates paracetamol-induced hepato- and nephrotoxicity via inhibition of CY2E1-mediated metabolism in rats
Ravindra Babu Pingili, Sridhar Vemulapalli, Uday Bhaskar Narra, Sree Varsha Potluri, Naveen Babu Kilaru
DOI: 10.7324/JAPS.2023.125993Pages: 096-104
Prospective pulmonary drug delivery system of pirfenidone microparticles for pulmonary fibrosis
Uqie Shabrina Hasyyati, Silvia Surini, Gatot Suhariyono Suhariyono
DOI: 10.7324/JAPS.2023.125985Pages: 095-105
An update on the pharmacology, phytochemistry, and toxicity of Myristica fragrans Houtt. as a source of treatment: A scoping review
Hilal Yaafi Elfia, Susilo Susilo
DOI: 10.7324/JAPS.2023.137812Pages: 092-106
Cytotoxic activity of Cyperus rotundus L. rhizome collected from three ecological zones in Lampung-Indonesia against HeLa cervical cancer cell
Nurul Utami, Susianti Susianti, Samsul Bakri, Betta Kurniawan, Arif Setiawansyah
DOI: 10.7324/JAPS.2023.113764Pages: 141-148
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Prebiotic fructooligosaccharides ameliorate the lipop olysaccharides-induced oxidative stress of mice brain
Shreya, Banalata Mohanty
DOI: 10.7324/JAPS.2023.159123Pages: 273-279
Anticancer property of marine coral-derived Streptomyces sp. SS162 against A549 lung adenocarcinoma cancer cells
Tran Hoang Ngau, Truong Thi Bich Ngoc, Le Thi Y. Nhi, Nguyen Hoang Chuong, Dang Thi Phuong Thao
DOI: 10.7324/JAPS.2023.144118Pages: 188-198
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Evaluation of antimicrobial, cytotoxicity effects and antioxidant potential of Stemodia verticillata (Mill.) Hassl extract
Alfredi A. Moyo, Sneha R. Bhosale, Kishor S. Jagadhane, Sachin B. Shinde, Vinod B. Shimpale, Prashant V. Anbhule
DOI: 10.7324/JAPS.2023.143858Pages: 119-130
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Free radical scavenging activities and nonessential trace toxic metals Al, Cd, Ni, and Pb contents of 22 herbal supplement products
Fazilatun Nessa, Saeed Ahmed Khan, Susan George, Fathima Suhara
DOI: 10.7324/JAPS.2023.93622Pages: 065-074
Anticancer and immunostimulatory activities of Houttuynia cordata Thunb. Extract and the isolated flavonoids: An in vitro/in vivo investigation
Tran Viet Hung, Phan Nguyen Truong Thang, Nguyen Thi Thu Phuong, Duy Toan Pham, Ha Minh Hien, Duyen Thi My Huynh
DOI: 10.7324/JAPS.2023.147199Pages: 178-187
Evaluation of Argyreia speciosa root extract as a protective agent against cyclophosphamide-induced toxicities
Alkesh Patel, Hardik Koria, Diwyanshi Zinzuvadia, Rushikumar Shah, Urmit Patel, Nandini Patel, Vithal Deshpande, Bhavna Parwani
DOI: 10.7324/JAPS.2023.136648Pages: 153-161
Pharmacokinetics and toxicology studies of new neuronal growth factor
Mir Sadat-Ali, Dakheel A Al-Dakheel, Khulood S. Al Ghamdi, Shahanas Chathoth, Fadel A. Al-Omar, Hassan A. Al Saad, Ayesha Ahmed
DOI: 10.7324/JAPS.2024.112811Pages: 120-124
Antimicrobial and cytotoxic properties of actinobacteria associated with a stony coral Fungia sp. from Karimunjawa National Park, Indonesia
Mada Triandala Sibero, Evan Hansel Frederick, Diah Permata Wijayanti, Dwi Haryanti, Anggun Puspitarini Siswanto, Yasuhiro Igarashi
DOI: 10.7324/JAPS.2024.139056Pages: 132-140
Identification and validation of potential genotoxic impurity in Rizatriptan by ultra performance liquid chromatography
Veeraswami Boddu, Rama Rao Rayala
DOI: 10.7324/JAPS.2024.152121Pages: 212-220
Impact of duration of infusion on estimated blood amikacin levels: A study at the Central General Hospital in Yogyakarta, Indonesia
Esti Dyah Utami, Ika Puspitasari, Rizka Humardewayanti Asdie, Endang Lukitaningsih, Andaru Dahesihdewi
DOI: 10.7324/JAPS.2024.80753Pages: 174-183
Evaluation of acute and subacute oral toxicity induced by ethanol extract of Boletus griseipurpureus Corner in male mice: Blood parameters and histopathological studies
Anussara Kamnate, On-Anong Somsap, Patcharin Singdam, Gornganok Piboonpol, Wanita Pantong
DOI: 10.7324/JAPS.2024.155387Pages: 184-191
Characterization of in vitro antimicrobial activity of gyrophoric acid isolated from Parmotrema indicum on methicillin-resistant Staphylococcus aureus
Thang Truong Le, Huy Thuc Duong, Chuong Hoang Nguyen
DOI: 10.7324/JAPS.2024.163764Pages: 045-054
Anticancer activity of ex vitro established Achillea thracica Velen. water extracts
Vanya Koleva, Asya Dragoeva, Zheni Dimitrova, Stefani Toshkova, Mariya Rogova
DOI: 10.7324/JAPS.2024.162200Pages: 171-175
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Cytotoxic constituents of Cymbidium tracyanum L.Castle
Nonthalert Lertnitikul, Rutt Suttisri, Khin Lay Sein, Suree Jianmongkol, Cherdsak Boonyong, Witchuda Thanakijcharoenpath
DOI: 10.7324/JAPS.2024.158840Pages: 112-119
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Nitric oxide production inhibitors from Polygonum multiflorum
Dao-Cuong To, Phi-Hung Nguyen, Viet Dung Hoang, Le Minh Hoang, Hoa Thi Nguyen, Truong Thi Viet Hoa, Truong Thi Thuy Nhung, Phu Chi Hieu Truong, Kim Thuong Pham Van
DOI: 10.7324/JAPS.2024.169653Pages: 130-135
Murraya koenigii L. Spreng.: An updated review of chemical composition, pharmacological effects, and toxicity studies
Yuvianti Dwi Franyoto, Arief Nurrochmad, Nanang Fakhrudin
DOI: 10.7324/JAPS.2024.169254Pages: 011-027
New bisnorsesquiterpene from Glottiphyllum linguiforme and its antimicrobial, cytotoxic, and antioxidant activities
Hayam S. Ahmed, Dalia El Amir, Hasan M. H. Muhaisen, Mohamed Sebak, Tamer M. Abdelghany, Abeer H. Elmaidomy, Elham Amin, Asmaa I. Owis, Mohamed A. A. Orabi, Naglaa Afifi
DOI: 10.7324/JAPS.2024.173477Pages: 097-104
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Toxicity and biodistribution of alginate-stabilized AgNPs upon 14-days repeated dose oral administration in mice
Dian Pribadi Perkasa, Wawaimuli Arozal, Kusmardi Kusmardi, Mukh Syaifudin, Tri Purwanti, Roza Indra Laksmana, Afiq Azfar Pratama, Irawan Sugoro, Dien Puji Rahayu
DOI: 10.7324/JAPS.2024.170167Pages: 135-146
Development of self-nanoemulsifying drug delivery system of 1-(2,5-dihydroxy phenyl)-3-pyridine-2-yl-propenone to enhance pro-apoptotic activities in MCF-7 breast cancer cells
Citra Ariani Edityaningrum, Andy Eko Wibowo, Dewa Ayu Arimurni, Yulia Rahmawati, Siti Fatmawati Fatimah, Laras Novitasari, Siti Khoirunnisa
DOI: 10.7324/JAPS.2024.145314Pages: 200-206
Anticancer activity of Celtis tournefortii Lam. against human liver cancer cells
Kavitha Krishna Nadiger, Valli Gunam, Rajagopal Kalyanaraman, Meenashree Balakrishnan, Kasturi Revathi, Sathya T. Narasimma Barathy
DOI: 10.7324/JAPS.2024.151332Pages: 231-236
Simultaneous use of Morinda citrifolia fruit extract and amlodipine: Antihypertensive activity and sub-chronic toxicity in rats
Nur Azizah, Irma Melyani Puspitasari, Aliya Nur Hasanah, Eli Halimah
DOI: 10.7324/JAPS.2024.163761Pages: 263-274
Characterization and safety assessment of Hydroxypropyl Musa paradisiaca starch for pharmaceutical applications
Samyuktha Metta, Suvendu Kumar Sahoo
DOI: 10.7324/JAPS.2024.174568Pages: 111-123
Innovative niosomal in-situ gel: Elevating ocular drug delivery synergies
Neha Kandpal, Rakshanda Dhuliya, Neha Padiyar, Abhishek Singh, Shivansh Khaudiyal, Yogita Ale, Vikash Jakhmola, Nidhi Nainwal
DOI: 10.7324/JAPS.2024.191581Pages: 001-017
The interconnections between gerontogen, aging, and senotherapy
Rahma Rahma, Agian Jeffilano Barinda
DOI: 10.7324/JAPS.2024.184140Pages: 042-052
Safety profile assessment of standardized root extract of Potentilla fulgens in Wistar rats: Acute and sub-acute dermal toxicity study
Suman Kumar, Yogesh P. Nikam, Sunayana Baruah, Susankar Kushari, Shatabdi Ghose, Satyendra K. Prasad, Asha Das, Zartaj Wasmin Banu, Junmoni Kalita, Damiki Laloo
DOI: 10.7324/JAPS.2024.184938Pages: 138-147
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The development of a GC-FID method for indirect quantification of chloroacetyl chloride, a potential genotoxic impurity, in chlordiazepoxide hydrochloride drug substance
Srinivas Birudukota, Bhaskar Mangalapu, Ramesha Andagar Ramakrishna, Swagata Halder, Venkata Narayana Palakollu
DOI: 10.7324/JAPS.2024.182017Pages: 196-207
Phytochemical analysis and in vitro investigation of wound healing, cytotoxicity, and inflammatory response in potentially active extracts of Anogeissus dhofarica
Duaa Abuarqoub, Walid Aburayyan, Luay Rashan, Wael Abu Dayyih, Hisham Y. Al-Matubsi
DOI: 10.7324/JAPS.2024.174429Pages: 152-162
Computational investigation into Parinari curatellifolia flavonoids as lead hepatoprotective therapeutics
Ayodeji Amobonye, Saheed Sabiu, Mary Tolulope Olaleye, Santhosh Pillai
DOI: 10.7324/JAPS.2024.188178Pages: 167-177
Endophytic fungi from red ginger (Zingiber officinale var. rubrum) as promising source of antimicrobial and cytotoxic secondary metabolites
Ni Putu Ariantari, Ni Putu Eka Leliqia, I Putu Yogi Astara Putra, Nadzifa Nugraheni, Riris Istighfari Jenie, Edy Meiyanto
DOI: 10.7324/JAPS.2024.178823Pages: 100-110
Anti-oxidative constituents of Musa balbisiana Colla fruit extract and evaluation of hepatoprotective activity in CCl4-induced hepatotoxicity in Swiss albino mice
Nabanita Baruah, Madhubanti Das, Kandarpa Kumar Saikia, Jogen Chandra Kalita
DOI: 10.7324/JAPS.2024.172339Pages: 111-119
Chemometric analysis of GC-MS chemical profiles and biological activities of three citrus essential oils in Indonesia
Einstivina Nuryandani, Erliana Novitasari, Muhammad Fatih Abdurrahman, Nurul Habibi, Ardiba Rakhmi Sefrienda, Dedy Kurnianto, Jasmadi Jasmadi, Yusuf Andriana
DOI: 10.7324/JAPS.2024.188353Pages: 187-195
Investigation of the antimicrobial efficacy and cytotoxicity of a natural disinfectant Syzygium cumini (L.) skeels leaf extract on vero cell lines
Haorongbam Joldy Devi, Prathiba Gnanasekaran, Yumnam Asha Devi, Durairaj Siva, Jaihitashee Jayashankar
DOI: 10.7324/JAPS.2024.203410Pages: 125-132
Development and application of an LC-MS/MS method for the detection of N-nitrosochlordiazepoxide as a potential genotoxic impurity
Srinivas Birudukota, Bhaskar Mangalapu, Ramesha Andagar Ramakrishna, Swagata Halder
DOI: 10.7324/JAPS.2025.199616Pages: 242-253
Anti-cancer activity and brine shrimp lethality assay of the extracts and isolated compounds from Garcinia schomburgkiana Pierre
Chanchai Sukkum, Chakkree Lekklar, Krisana Chongsri, Sataporn Deeying, Chantragan Srisomsap, Nakin Surapanich, Pronrumpa Kanjanasingh, Sakchai Hongthong
DOI: 10.7324/JAPS.2025.209800Pages: 241-247
Chiral properties of zinc complexes with bi- and tridentate ligands of L- and D-amino acids
Vladimir N. Tumasov, Alla V. Marukhlenko, Quynh T.N. Hoang, Anton P. Novikov, Alena M. Koldina, Mariya A. Morozova
DOI: 10.7324/JAPS.2025.209656Pages: 043-052
In silico screening and experimental validation of Carissa carandas L. extract against cyclophosphamide-induced cardiotoxicity in Wistar rats
Roopadevi Desaipatti, Namit Kudatarkar, Sachin Gudasi
DOI: 10.7324/JAPS.2025.198181Pages: 248-259
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Harnessing the potential of TiO2 nanoparticles from marine macroalgae Ulva lactuca for antibacterial, anti-inflammatory, and cytotoxic properties
Mohamed Sitheeq Afra Mariyam, Subburayan RR, Ganapathy Dhanraj
DOI: 10.7324/JAPS.2025.223793Pages: 135-141
Betula utilis (Bhojpatra): A potent herb with its traditional uses, phytochemistry, clinical application, pharmacology, and toxicology
Aanchal Loshali, Garima Tripathi, Sandhya Bawa, Vidhu Aeri
DOI: 10.7324/JAPS.2025.230627Pages: 001-013
Development of pentagamavunon-1 complexes with glycated albumin for targeted drug delivery: Synthesis, characterization, and cytotoxicity in cancer cells
Fea Prihapsara, Edy Meiyanto, Khadijah, Anif Nur Artanti, Adam Hermawan
DOI: 10.7324/JAPS.2025.221096Pages: 129-137
Subchronic toxicological evaluation of the Holothuria atra extract on the histopathology of digestive organs of rats (Rattus norvegicus)
Muhammad Nursid, Endar Marraskuranto, Ariyanti S. Dewi, Gintung Patantis, Tiara Silva Khatulistiani, Yann Yeo, Sri Estuningsih
DOI: 10.7324/JAPS.2025.216477Pages: 163-175
Central composite design enabled formulation development, optimization, and characterization of bosutinib monohydrate loaded lipid nanoparticles: Cytotoxicity studies
Dhananjay Panigrahi, Surya Kanta Swain, Bikash Ranjan Jena, Prasanna Parida, Pratap Kumar Sahu
DOI: 10.7324/JAPS.2025.228972Pages: 137-155
LC-HRMS profiling and in vitro total phenolics, total flavonoids, antioxidant and cytotoxicity evaluation on MCF7 breast cancer cell lines of the extracts and fractions of Aerva sanguinolenta from Java, Indonesia
Armansyah Maulana Harahap, Kurnia Agustini, Nuralih Nuralih, Sri Ningsih, Yuli Widyastuti, Anton Bahtiar
DOI: 10.7324/JAPS.2025.227288Pages: 265-276
Fabrication, biodistribution, and toxicological evaluation of mesoporous silica nanoparticles based on preclinical studies intended for cancer therapy: A review
Muhammad Esa, Sunisa Kaewpaiboon, Teerapol Srichana
DOI: 10.7324/JAPS.2025.220858Pages: 001-026
Protective effects of pterostilbene, purpurin, and arbutin on liver damage in diabetic and non-diabetic rodents
Onkar Bedi, Niharika Srivastava, Davinder Parsad, Tanuj Hooda, Amit Lather, Amarjot Kaur Grewal, Thakur Gurjeet Singh, Gulsheen Panesar, Manish Kumar, Pawan Krishan
DOI: 10.7324/JAPS.2025.221655Pages: 295-310
Anti-leishmanial potential of Betula utilis D. Don ethanolic extract, isolated betulin and its ester derivative on THP-1cells against Leishmania donovani
Aanchal Loshali, Mirza Adil Beg, Sandhya Bawa, Angamuthu Selvapandiyan, Vidhu Aeri
DOI: 10.7324/JAPS.2025.241438Pages:
