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Overview of novel sample pretreatment methods and their pharmaceutical applications in bioanalysis

Jamshed Haneef, Larzi Mohsin Bin Mohammed

DOI: 10.7324/JAPS.2026.241408

Sesbania grandiflora (L.) Pers.: A review of its phytochemistry, molecular pharmacology, and clinical potential

Vijishna Lekshmi Viswambharan, Manoj Madanahalli Ramesh, Rudresh Adarkar, Maria Nison, Megha Kotian, Vasudev R. Pai, Chandrashekhar K. S. Bhat, Richard Lobo

DOI: 10.7324/JAPS.2026.276745

Cape gooseberry (Physalis peruviana L.) as a functional food for metabolic health: A narrative review of glucose and lipid regulatory effects

María Gabriela Mendoza-Girón, Fernando Castro-Gómez, Jenny Castro Guerrero

DOI: 10.7324/JAPS.2026.260089

Cell and Gene Therapy Regulation in Malaysia: Current Pathways and International Comparison

Hazureen Mohd Halimi, Meor Mohd Redzuan Bin Meor Mohd Affandi, Mahmathi Karuppannan, Azizah Ab. Ghani

DOI: 10.7324/JAPS.2026.248204

Development of a HPLC method for the quantification of Docetaxel in the BPMO@DTX injectable formulation

Ha Van Nguyen, Quan Minh Le, Tuan Duc Nguyen, Ngan Hanh Thao Nguyen, Minh Cong Duong, Anh Nhat Ha, Trinh Thu Thi Le, Dang-Khoa Nguyen, Tan Le Hoang Doan, Tri Minh Le

DOI: 10.7324/JAPS.2026.252951

Morin protects against palmitic acid-induced diabetic cardiomyopathy via SIRT6 activation and mitochondrial preservation

K. P Divya, P. V Anuranjana, Krupa Thankam George, Krishnaprasad Baby, Fathima Beegum, Navjot Kanwar, Nitesh Kumar, Krishnadas Nandakumar, Abhinav Kanwal

DOI: 10.7324/JAPS.2026.261812

Aaptamine attenuates the action of statin on PCSK9 and LDLR expression as well as LDL-C uptake in human liver cells

Abdul Matin, Gul-e-Saba Chaudhry, Yeong Yik Sung, Tengku Sifzizul Tengku Muhammad

DOI: 10.7324/JAPS.2026.26400

Solid lipid nanoparticle-loaded oral dispersible films of eletriptan hydrobromide for enhanced bioavailability and sustained migraine relief

Anju Bala, Chander Parkash Dora, Inderjeet Verma

DOI: 10.7324/JAPS.2026.262961

A retrospective observational study on the discordance rate of antibiotic dosing among critically ill patients: Considerations for using KDIGO guideline

Worapong Sungsana, Chotirat Nakaranurack, Weerachai Chaijamorn, Nattachai Srisawat

DOI: 10.7324/JAPS.2026.259994

A sensitive green analytical LC-MS/MS method for the quantification of trace levels of nine nitrosamine impurities in Zaltoprofen bulk drug

Shobha Rani Satla, Raghuvaran Gunda

DOI: 10.7324/JAPS.2026.244232

Formulation development of diclofenac sodium extended-release tablet using hydrophobic and hydrophilic matrix systems

Truc-ly Thi Duong, Duyen Thi My Huynh, Tu-Uyen Thi Nguyen, Quoc-Dung Tran Huynh, Thuy-Tien Thi Phan, Thu-Thi Tran, Ha Van Nguyen, Benni Iskandar, Dang-Khoa Nguyen

DOI: 10.7324/JAPS.2026.253028

Bioanalytical method development and validation for the pharmacokinetics and biodistribution study of pirfenidone-loaded solid lipid nanoparticles

Suci Ananda Putri, Yahdiana Harahap, Silvia Surini

DOI: 10.7324/JAPS.2026.231524

Red rice bran extract attenuates oxidative stress and testicular damage in high-fat diet/streptozotocin-induced diabetic rats

Watcharaporn Preedapirom Jeefoo, Atcharaporn Ontawong, Sirinat Pengnet, Tichanon Promsrisuk, Napapan Kangwan, Wathita Phachonpai, Arnon Pudgerd

DOI: 10.7324/JAPS.2026.249609

Discovery of pyrazole–pyrazoline derivatives as VEGFR-2 kinase inhibitors: In silico approach

Deepali M. Wanode, Kumud P. Bhendarkar, Pramod B. Khedekar

DOI: 10.7324/JAPS.2026.256031

Quinazolinone derivatives as selective COX-2 inhibitors: In silico analysis using molecular docking, dynamics, and ADMET

Tendy Oktriawan, Tri Joko Raharjo, Winarto Haryadi, Muhammad Idham Darussalam Mardjan

DOI: 10.7324/JAPS.2026.235134

Immunogenicity evaluation of an Alum-adjuvanted recombinant prefusion RBD-Fd SARS-CoV-2 protein subunit produced in Glycoengineered Pichia pastoris

Andri Wardiana, Hariyatun Hariyatun, Dian Fitria Agustiyanti, Yana Rubiyana, Alfi Taufik Fathurahman, Herjuno Ari Nugroho, Endah Puji Septisetyani, Popi Hadi Wisnuwardhani, Sugiyono Saputra, A’liyatur Rosyidah, Syaiful Rizal, Hastuti Handayani S. Purba, Kartika Sari Dewi, Nissa Arifa, Ratih Asmana Ningrum, Wien Kusharyoto

DOI: 10.7324/JAPS.2026.270912

Metabolite profiling and bioactivity of Pogostemon cablin L. from North Konawe: GC-MS analysis, anti-inflammatory, and antinociceptive mechanisms via COX-2/cytokine inhibition

Adryan Fristiohady, Jafriati, Irvan Anwar, Rathapon Asasutjarit, Idin Sahidin, Sry Susanti, Lidya Agriningsih Haruna, La Ode Muh Julian Purnama, Hariana, Hutamy Viranda Rahman

DOI: 10.7324/JAPS.2026.268636

Challenges of using Artificial Intelligence (Natural Language Processing) tools for regulatory documentation

Harshada B. Pawar, Neelanshu, Gowri M. Bhat, Arun Srikanth, Pradeep M. Muragundi

DOI: 10.7324/JAPS.2026.267918

Hypoglycemic potential of Sargassum spp.: A review of bioactive compounds for diabetes management

Muhamad Firdaus, Ahmad Faris Priambodo

DOI: 10.7324/JAPS.2026.234652

Gut microbiota as a key player in type 2 diabetes: Current perspectives

Sruthi Sethumadhavan, Saramma Mini Jacob, Monica Narendra Babu

DOI: 10.7324/JAPS.2026.267236

Traditional Vietnamese herbal remedies treatments for Gout: A comprehensive review of mechanisms, practical applications, and therapeutic potential

Hung Minh Hoang, Ling Yan Yong, Khang Hoang Au, Tuan Minh Pham, Van Anh Thi Pham, Thu Hien Thi Dang, Yong Xiang Gao

DOI: 10.7324/JAPS.2026.254687

Phytochemical and pharmacological profile of Aegle marmelos (L.) Correa: A comprehensive review of therapeutic potential, mechanisms of action, and translational relevance

Amitha Shetty, Lowel Fernandes, Devendranath Shambhavi, Manohar Mahadev, Akhilesh Dubey

DOI: 10.7324/JAPS.2026.273299

Microbial nanoparticles: biosynthesis and emerging roles in combating antimicrobial resistance

Alan Raj, Angel Treasa Alex, Venkatesh Kamath, Volety Mallikarjuna Subrahmanyam

DOI: 10.7324/JAPS.2026.244963

Development of a validated LC-ESI-MS/MS method for the quantification of tucatinib in plasma samples

Sunil Dattatray Pawar, Deepak D. Kayande, Kokila Pawar, Mazahar Farooqui, Anil Shankarwar, Amol Deshpande, Sunil Shankarwar

DOI: 10.7324/JAPS.2025.213916

Agitation-assisted extraction of total phenolic and flavonoid compounds from lanche leaves [Myrcianthes discolor (Kunth) McVaugh]: Influence of solvent ratio and its impact on antioxidant activity

Juan Ernesto Valdiviezo-Campos, Cinthya Stephany Neglia Cermeño, Segundo Guillermo Ruiz-Reyes

DOI: 10.7324/JAPS.2025.243158

Salacia oblonga aqueous root extract restores β-cell function in experimental diabetes via antioxidant effects and MAFA upregulation

Senthil Kumar Anbumani, Manickam Subramanian, Sharmila Aristotle, Prabhu Kaliyaperumal

DOI: 10.7324/JAPS.2025.264678

Pharmacogenomics for sustainable drug development: A narrative review of precision medicine, green chemistry, and multi-omics innovation

Kanagaraj Lakshmi, Balaji Nagarajan, Kumaraswamy Dabburu, Chittran Roy, Balasubramanian Shanthi, Gunamoni Das, Tamalika Chakraborty, Shamina Syed, Joshua Albert, Kannaiyan Suria Prabha

DOI: 10.7324/JAPS.2025.260740

Thermotropic liquid crystals for precision drug delivery and diagnostics: Molecular design, characterization, and clinical translation

Anjana A. Kailas, K.A. Abutwaibe, Poornima Bhagavath, Debanjan Bhattacharjee, Annamalai Rama, Induja Govindan, Thamizharasan Annadurai, Anup Naha

DOI: 10.7324/JAPS.2025.255035

Enhanced oral delivery of epigallocatechin gallate via expanding gastro-retentive films composed of chitosan and konjac glucomannan blends

Arnas Lakhiew, Rachanida Praparatana, Yaowaporn Sangsen, Ruedeekorn Wiwattanapatapee

DOI: 10.7324/JAPS.2025.251914

Regulation of estrogen receptor-mediated apoptosis by vitexin in human colorectal carcinoma cells

Surekha Vani, Bhagavathy Sivathanu

DOI: 10.7324/JAPS.2025.261688

Ethanolic root extract of Bouea macrophylla Griffith improves lipid homeostasis in palmitate-induced lipid accumulation in HepG2 cells

Linda Chularojmontri, Jarinyaporn Naowaboot, Urarat Nanna, Kusuma Jitsaeng, Thaweesak Juengwatanatrakul, Suvara Wattanapitayakul, Wanwisa Suwannaloet

DOI: 10.7324/JAPS.2025.250674

Mechanistic insights into the anti-aging potential of Centella asiatica via network pharmacology and molecular docking

Cut Shafa Safira, Raymond Rubianto Tjandrawinata, Adi Yulandi

DOI: 10.7324/JAPS.2025.240042

Biological prospecting of endophytic fungi from the stem bark of Oroxylum indicum (L.) Kurz with antioxidant efficacy

Sushma, Apoorva Kenjar, Juliet Roshini Mohan Raj, Vishakh Radhakrishna Kedilaya, Tamizh Selvan Gnanasekaran, Pavan Gollapalli, Sharmila Kameyanda Poonacha

DOI: 10.7324/JAPS.2025.247093

Identification of thiazolidin-4-one scaffold-based molecules as PI3Kα inhibitors: Molecular docking, MM/GBSA, IFD, ADMET, water-map analysis, and MD simulations

Keezhe Perumpadappu Krishnan, Kasaragod Mangala Shenoy, Suvarna Ganesh Kini, Ramaiah Selladurai Jeyaprakash

DOI: 10.7324/JAPS.2025.253482

Formulation development and optimization of nanoemulsion gel containing Prosopis cineraria, Aerva javanica, and Fagonia indica extracts for treatment of arthritis

Suman Jain, Abhishek Pandey

DOI: 10.7324/JAPS.2025.241266

Supercritical fluid extraction, LC-MS profiling, and QbD-guided green HPLC method for standardization of Careya arborea Roxb. nanoemulsion

Abhijit S. Salokhe, Archana S. Patil, Yadishma Gaude, Pooja Rayanade, Rahul Koli, Namdeo S. Jadhav

DOI: 10.7324/JAPS.2025.266427

Antihyperglycemic and hypoglycemic activities of Castanopsis costata: An experimental study with in vitro, in vivo, and histopathological evaluation

Maulana Yusuf Alkandahri, Asman Sadino, Wilda Fhitriany Usman, Eva Feriadi, Zulpakor Oktoba, Atri Sri Ulandari, Ana Yulyana, Annis Fathurrohmah, Shofa Khairunnisa, Indah Sari Amanatun Nisa, Annisa Rizqya Salmaduri

DOI: 10.7324/JAPS.2025.264681

Preformulation study as a basis for the development of Streptomyces sp. PNM-9 microparticles for biological control

Juan Ricardo Urrego, José David Tordecilla, Freddy Alejandro Ramos, Leonardo Castellanos, Carlos Alberto Bernal, Claudia Milena Baena-Aristizábal

DOI: 10.7324/JAPS.2025.257753

An ethnobotanical study of Indonesian medicinal plants to treat obesity

Devi Safrina, Nur Rahmawati Wijaya, Dian Susanti, M. Bakti Samsu Adi, Aditya Dwi Permana Putra, Sri Sulasmi, Rizal Maarif Rukmana, Pujiati Pujiati, Harto Widodo

DOI: 10.7324/JAPS.2025.229638

Network pharmacology and molecular dynamics studies unveil the therapeutic mechanisms of Zingiber officinale against dyspepsia

Stefeny Theresia Simatupang, Doni Dermawan, Nadia, Santi Tan, Raymond Rubianto Tjandrawinata

DOI: 10.7324/JAPS.2025.240961

Phytochemical and pharmacological aspects of the genus Chamaecrista: a systematic review

Domitila Villalba, Melissa Escobar, Cinthia Cazal Martínez, Javier E. Barúa, Fillipe De Oliveira Pereira, Juliana Moura-Mendes

DOI: 10.7324/JAPS.2025.241066

Medication reconciliation and its essentiality in the geriatric population: A comprehensive review

Abubakar Siddique Mustafa Hussain, Syed Azhar Syed Sulaiman, Safiya Fatima Khan, Waad Alrohily, Siti Maisharah Sheikh Ghadzi, Saud Mohammad Alsahali, Yaser Mohammed Al Worafi

DOI: 10.7324/JAPS.2025.235827

Optimization using response surface methodology and analysis of antimicrobial activity of pink pigmented Fusarium foetens CBS 110286

Bashir Ahmad Aliyu, Shashank Garg, Sawinder Kaur, Ashish Vyas

DOI: 10.7324/JAPS.2025.260601

Quantification of asciminib by LC-MS/MS method in human plasma: Validation and stability studies

Hema, Naresh Panigrahi

DOI: 10.7324/JAPS.2024.163326