This review article is focused on different synthetic strategies used in dendrimer synthesis at commercial and laboratory scale. These synthetic strategies includes their own advantages and disadvantages. This review will cover divergent (from core to surface) and convergent (from surface to core) approaches used in dendrimer synthesis and the problems associated with these synthetic strategies. This article also covers the important applications of dendrimers in the field of pharmaceutical sciences. This data of review is collected from various articles, research papers and patents available on dendrimers.