Patients have a right to privacy thus; all the studies should be conducted with informed consent. No identifying information should be published in written descriptions, photographs, and pedigrees unless the information is essential for scientific purposes and the patient (or parent or guardian or legally authorized representative) gives written informed consent for publication. When informed consent has been obtained, it should be indicated in the article. Investigations with human subjects must follow the ethical standards formulated in the Helsinki Declaration of 1964, revised in 2000. All the experiments should be approved by the institutional human experimentation committee or equivalent.
Note: Please do not submit the patient’s actual written informed consent with your article, as this in itself breaches the patient’s confidentiality. The authors need to include a statement regarding the same in the manuscript text.
Animal experiments must follow the ethical standards for the care and use of laboratory animals. The article involved the animal experiments must seek approval from the appropriate Ethical Committee in accordance with "Principles of Laboratory Animal Care" (NIH publication no. 85-23, revised 1985).
Clinical trial registry
We advise the authors to register the clinical trials with a clinical trial registry that allows free online access to the public. Registration in the following trial registers is acceptable:
http://www.trialregister.nl/ and http://www.umin.ac.jp/ctr.