Research Article | Volume: 5, Issue: 9, September, 2015

In vitro evaluation of Schima wallichii (DC.)Korth.fruit for potential antibacterial activity

Ankur Das Barma Jyochhana Priya Mohanty Prosanta Pal Nihar Ranjan Bhuyan   

Open Access   

Published:  Sep 27, 2015

DOI: 10.7324/JAPS.2015.50923
Abstract

Schima wallichii (DC.) Korth. is a large evergreen and well known tree of Sikkim Himalayan region. The bark of this plant is traditionally used as antipyretic, antiseptic, anthelmintic, wound healing agent. In the present study an attempt has taken to investigate for potential antibacterial activity by taking different extracts of fruits of Schima wallichii (DC.) Korth. against Gram-positive bacteria (Staphylococcus aureus NCTC 8530 and Bacillus liherfernis 10341) and Gram-negative bacteria (Escherichia coli HD10; Salmonella paratyphi A2 and Vibrio cholera 64). Antibacterial activity of Schima wallichii (DC.) Korth. fruit extracts (benzene, acetone and aqueous) were assayed by the disc diffusion method. Among all the extracts, acetone extract was found most active against Escherichia coli HD10 and Bacillus liherfernis 10341 but this extract have no effect in case of Vibrio cholera 64. The MIC (Minimum Inhibitory Concentrations) of the extract was found 100 µg/ml for Escherichia coli HD10 and 150 µg/ml for Bacillus liherfernis 10341. The study promises an interesting future for designing a potentially active antibacterial agent from Schima wallichii (DC.) Korth. fruit.


Keyword:     Schima wallichii (DC.) Korth. fruit antibacterial activity agar disc diffusion assay minimum inhibitory concentration (MIC).


Citation:

Barma AD, Mohanty JP, Pal P, Bhuyan NR. In vitro evaluation of Schima wallichii (DC.)Korth.fruit for potential antibacterial activity. J App Pharm Sci, 2015; 5 (09): 124-126.

Copyright:The Author(s). This is an open access article distributed under the Creative Commons Attribution Non-Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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